M. Lyon, J. Groathouse, J. Beaber, L. M. Turner, K. A. Rouhier, M. V. Wilson, D. J. Symonsbergen, S. M. Sikich and A. E. Holmes, “DETECHIP: An Improved Molecular Sensing Array,” Journal of Forensic Research, Vol. 2, No. 126, 2012, pp. 1-7.

has been cited by the following article:

• TITLE: Detecting Concentration of Analytes with DETECHIP: A Molecular Sensing Array

  AUTHORS: Hannah Johnke, Gary Batres, Mark Wilson, Andrea E. Holmes, Sharmin Sikich

  KEYWORDS: Colorimetric Arrays; Sensors; Analyte Concentration; RGB Analysis; Drug Detection

  JOURNAL NAME: Journal of Sensor Technology, Vol.3 No.3, September 12, 2013

  ABSTRACT: DETECHIP is a detection system made of various sensors that has been shown to detect and discriminate between small molecules of interest, including various illicit and over-the-counter drugs. Previously, detection was normalized to a single concentration of analyte. Now this detection assay can detect concentration differences in analytes via red, green, and blue color value changes and shifts in the UV-Vis spectra of the assay. To determine the concentrations differences, the exposed assays were scanned on a flatbed scanner and the images were analyzed for individual RGB values with a custom macro in ImageJ, an image analysis program. Increasing concentrations of the analyte resulted in greater differences in color values between control and analyte wells. These differences showed a linear relationship to concentration change, some with correlation coefficients greater than 98%. This work expands the capability of DETECHIP to give information about the concentration of analyte when the analyte identity is known.