Article citationsMore>>
Gauci, M.L., Laly, P., Vidal-Trecan, T., Baroudjian, B., Gottlieb, J., Madjlessi-Ezra, N., Meda, L.D., Madelaine-Chambrin, I., Bagot, M., Basset-Seguin, N., Pages, C., Mourah, S., Boudou, P., Lebbé, C. and Gautier, J.F. (2017) Autoimmune Diabetes Induced by PD-1 Inhibitor—Retrospective Analysis and Pathogenesis: A Case Report and Literature Review. Cancer Immunology, Immunotherapy, 66, 1399-1410.
https://doi.org/10.1007/s00262-017-2033-8
has been cited by the following article:
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TITLE:
Long-Term Persistent Absolute Insulin Secretion Deficiency in Diabetes Induced by Immune Checkpoint Inhibitors
AUTHORS:
Moctar Bah, Clara Bouché, Jean-François Gautier
KEYWORDS:
Immune Checkpoint Inhibitors, Nivolumab, Ipilimumab, Fulminant Diabetes, Insulin-Requiring Diabetes
JOURNAL NAME:
Open Journal of Endocrine and Metabolic Diseases,
Vol.13 No.12,
December
27,
2023
ABSTRACT: Immune checkpoint inhibitors are today an immense hope in the management
of cancers. However, since their widespread use, many cases of
insulin-requiring diabetes appearing suddenly, as fulminant diabetes have been
reported. Here, we describe 4 cases that occurred at different times after the
beginning of immune checkpoint inhibitor therapy with Nivolumab alone or
associated with Ipilimumab. There are 3 cases of newly diagnosed diabetes and 1
case of known type 2 diabetes formerly quite well balanced with Metformin. The
clinical and biological characteristics of these patients are quite similar.
They were all insulin-requiring at the discovery of diabetes and remained so
throughout their follow-up. This type of diabetes which looks like type 1
diabetes seems rather to be a new entity.
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