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has been cited by the following article:

• TITLE: The Whole Story: A Comprehensive Review of Whole Blood Resuscitation for Hemorrhagic Shock

  AUTHORS: Abdullah S. Al-Darwish, Zaid A. Althowimer

  KEYWORDS: Whole Blood Resuscitation, Hemorrhagic Shock, Animal Studies, Clinical Trials

  JOURNAL NAME: Open Access Library Journal, Vol.10 No.8, August 8, 2023

  ABSTRACT: Whole blood resuscitation has emerged as a promising alternative to conventional component therapy for patients in hemorrhagic shock. Animal studies and clinical evidence in both civilian and military populations have shown improved outcomes with whole blood. While further research is needed to establish optimal patient selection criteria, dosing, and transfusion practices, the use of whole blood in resuscitation has the potential to save lives and improve outcomes. Whole blood provides balanced levels of red cells, plasma, and platelets, mimicking normal physiology and sealing leaks in the clotting cascade that often develop. The available clinical evidence suggests that whole blood resuscitation may provide advantages over component therapy in certain patient populations and clinical settings.