TITLE:
Diabetes Mellitus and COVID-19 at Abass Ndao Hospital Epidemic Treatment Center (ETC)
AUTHORS:
Diallo Ibrahima Mané, Diédhiou Demba, Ndour Michel Assane, Sow Djiby, Diallo Adja Tacko Mané, Dieng Mouhamed, Gadji Fatou Kiné, Thioye El Hadji Mamadou Moussa, Bassène Joseph, Ndiaye Ndeye Fama Mody, Sarr Anna, Ndour Mbaye Maimouna
KEYWORDS:
Abass Ndao, Diabetes Mellitus, ETC, SARS-CoV-2, Senegal
JOURNAL NAME:
Open Journal of Endocrine and Metabolic Diseases,
Vol.12 No.4,
April
21,
2022
ABSTRACT: Introduction: SARS-COV2 infection is a major public health problem and diabetes
mellitus is a serious factor. The objective was to determine the characteristics of COVID-19 in diabetics at the
Epidemic Treatment Center (ETC) of the Abass Ndao Hospital Center. Observation: This was a retrospective, descriptive and
analytical study carried out at Abass Ndao Hospital from March 01, 2021 to September 31, 2021. We evaluated
the epidemiological, clinical and evolutionary characteristics. Results: Among 333 patients infected with COVID-19, 203 were diabetic (60.96%). The sex
ratio was 0.70 and the mean age 60.18 years.
Diabetes was type 2 (84.2%) and inaugural (15.8%). Arterial hypertension
was the main comorbidity (86.96% of cases). The
RT-PCR test was positive in 86.21% of cases. The main clinical signs
were: asthenia (90.14%), dyspnea (78.81%),
cough (52.21%) and body aches (52.21%). Oxygen saturation was alanced
in 71.43% with an average blood sugar of 2.02 ± 4 g/l. At the paraclinical, the D dimer was ≥1000 ng/l (71.52%) and the
C-reactive protein ≥100 mg/l (32.01%). Chest CT scan found mild to moderate
(55.17%), severe (21.67%) and critical (17.24%) lung lesions. Pulmonary
embolism was found in 4 diabetics. The
treatment of diabetes was represented by insulin therapy (85.82%) and
oral antidiabetics (24.11%). Anti-COVID-19 treatment was dominated by
azithromycin (89.11%), corticosteroid therapy (92.11%), anticoagulants (99%),
hydroxychloroquine (21.29%). Mortality was found in 14.36% (n = 29) and significantly correlated with age ≥ 60 years
(OR = 3.013 [1.266 - 7.173], P = 0.005), short duration of
hospitalization (OR = 3.154 [1.149 - 8.663], P = 0.009), C-reactive protein > 100 mg/l (OR = 6.370 [2.704 - 15.006], P [2.633 - 15.222], P [3.367 - 18.322], P Conclusion: Diabetes
is one of the most important comorbidities
linked to the severity of SARS-CoV-2 infection. The seriousness factors
in this field remain age ≥ 60
years, lung damage ≥ 50%, CRP ≥ 100 mg/l, and oxygen saturation at 90%.