Granati, B., Felice, M., Fortunato, A., Giancola, G. and Rubaltelli, F.F. (1983) Sites of Action of Light during Phototherapy. Neonatology, 43, 1-8.
https://doi.org/10.1159/000241630
-
TITLE:
Ghost Haemoglobin Affecting the Efficacy of Phototherapy
AUTHORS:
Azizullah Langah, Sara Sadiq, Ali Akbar Siyal
KEYWORDS:
Hyperbilirubinemia, Neonatal Jaundice, Phototherapy
JOURNAL NAME:
International Journal of Clinical Medicine,
Vol.10 No.10,
October
15,
2019
ABSTRACT: Introduction: Phototherapy is the treatment of choice for neonatal hyperbilirubinemia. It converts the unconjugated bilirubin from polar and neurotoxic Z-Z-bilirubin to the more polar photobilirubin. It has been hypothesized that high level of hemoglobin or hematocrit interferes in the effectiveness of phototherapy. The objective of the current study is to find out the association of hemoglobin/hematocrit to change in total serum bilirubin concentration during phototherapy. Methods: A prospective cohort study was conducted on 296 neonates with uncomplicated hyperbilirubinemia. Before initiating the phototherapy, hemoglobin, hematocrit and total serum bilirubin levels were measured. After treating the neonates with phototherapy using LED-light for 24 hours, the total serum bilirubin level was measured again. The data were analyzed by using SPSS version-20. Results: The majority of study participants were male (60.8%), with mean postnatal age of 4.66 ± 1.65, having mean birth weight of 2.41 ± 0.41. Considering Pearson correlation, the hemoglobin had a significant inverse association with ΔTsB0-24 while birth weight and postnatal age also had inverse association but p-values were non-significant, while TsB0 had presented a very weak but significant positive association. The results might be evident of the fact that increase in hemoglobin concentration results in minimal change in total serum bilirubin concentration during phototherapy. Conclusion: Current study found a significant effect of hemoglobin on efficacy of phototherapy, as the change in total serum bilirubin concentration is inversely correlated with the level of hemoglobin. This is important for the physician in treating neonates with hyperbilirubinemia by using phototherapy.
Related Articles:
Voluminous Goiters in Surgery B of Chu of Point G: Diagnostic Aspects
S. Diallo, O. Sacko, L. Soumaré, M. Coulibaly, A. Kanté, B. Coulibaly, B. Togola, B. Bengaly, D. Ouattara, S. Sanogo, J. Saye, C. A. S. Touré, S. Koumaré, M. Camara, S. Keita, M. Sissoko, D. Traoré, N. Ongoiba
DOI:
10.4236/ss.2019.109034
172 Downloads 307 Views Citations
Pub. Date:
September
18,
2019
Surgical Treatment of Secondary Hyperparathyroidism in Surgery B of Chu of Point G
S. Diallo, O. Sacko, M. Sissoko, A. Kanté, A. Coulibaly, L. Soumaré, B. Coulibaly, M. Camara, D. Traoré, N. Ongoiba
DOI:
10.4236/ss.2019.1010039
373 Downloads 497 Views Citations
Pub. Date:
October
9,
2019
