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has been cited by the following article:

• TITLE: Combined Hepatocellular-Cholangiocarcinoma with Stem Cell Features—Case Report

  AUTHORS: Leonardo Verza, Carlos Henrique Rosas, Gabriel Marques Neves, Tércia Neves, Maria Dirlei Begnami, Marcos Duarte Guimarães

  KEYWORDS: Hepatocellular Carcinoma, Cholangiocarcinoma, Liver Neoplasm, Diagnostic Imaging

  JOURNAL NAME: Case Reports in Clinical Medicine, Vol.7 No.10, October 29, 2018

  ABSTRACT: Combined hepatocholangiocarcinoma is a rare and unique form of primary hepatic neoplasm, expressing histopathological and phenotypic aspects of hepatocellularcarcinoma and cholangiocarcinoma in the same tumor. Diagnosis may be performed by imaging, showing typical features of both components. We present a case of a 55-year-old woman presenting with abdominal pain and a hepatic mass. The patient underwent surgery and combined hepatocholangiocarcinoma with stem cells features was confirmed on pathological analysis. There are no signs of recurrence to date. Combined hepatocholangiocarcinoma requires a preoperative diagnosis, since it is a unique entity with higher rates of local and lymph node recurrence, compared to isolated forms.