TITLE:
The Effect of Gold Nanoparticle on Absorbed Dose by IMRT in Esophagus Phantom
AUTHORS:
Zeinabnamazi Shiraazi, Seyedrabie Mahdavi, Mohammad Mahdavi, Mahboubeh Khadem Abolfazli
KEYWORDS:
IMRT, Dosimetry, Gold Nanoparticle, Esophagus Phantom
JOURNAL NAME:
Open Access Library Journal,
Vol.2 No.9,
September
29,
2015
ABSTRACT:
This study aimed to evaluate the use of dosimeters MAGICA gel impregnated
with nanoparticles of gold to increase the dose of faulty tissue in the chest
phantom in the esophagus and other organs to determine the dose and dose
distribution in the tissue with an IMRT treatment. In this study, based on
previous studies, the optimal concentration of 0.1 mM gold nanoparticles has
been considered. Also, better localization and avoid radiation received dose by
other organizations around the IMRT machine used for radiation. For comparison
and understanding of dose distribution and dose rate increase factor (DEF), gel
dosimeters were acquired by MRI. The results showed that by adding gold
nanoparticles with a diameter of 50 nm and optimum concentration is 0.1 mM, the
dose and energy 500 cGy and 6 MV with IMRT respectively, the factors increasing
the dose (DEF) is about 9.74%. It’s remarkable, this research is that Esophagus
phantom to containing gold nanoparticles to other tissues (lung and spinal
cord) and also the Phantom of the esophagus in the absence of gold
nanoparticles, has received the highest dose and compared with the non-nano R2 Increased. It is also a good match between the results of dosimetry gel and
results of treatment.