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http://dx.doi.org/10.1073/pnas.87.15.5788

has been cited by the following article:

• TITLE: Helical Repeats of Left-Handed DNA

  AUTHORS: Youcheng Xu

  KEYWORDS: Left-Handed DNA, Ambidextrous Double Helix, Linking Number, Positive Supercoiling, Hyperthermophiles

  JOURNAL NAME: Open Journal of Molecular and Integrative Physiology, Vol.4 No.2, May 16, 2014

  ABSTRACT: DNA is generally assumed as a right-handed double helix and Z-DNA is a special kind of left-handed DNA infrequently found in nature. However, the finding of a zero linking number topoisomer supports a hypothesis that the two strands of DNA are winding ambidextrously, rather than plectonemically. It logically leads to a notion that the left-handed DNA is as common as right-handed DNA and the amount of left-handed DNA in a positively supercoiled plasmid prevails that of the right-handed DNA. In this report, the helical repeat of left-handed DNA, 12 bp per turn, was determined by a new method. How the positively supercoiled DNA was generated in hyperthermophiles and why their DNA can withstand the extreme high temperature are answered from an alternative theory.