Barel, A.O., Courage, W. and Clarys, P. (1995) Suction method for measurement of skin mechanical properties The Cutometer. In Serup, J. and Jemec, G.B.E. Eds., Handbook of Noninvasive Methods and the Skin, CRC Press, Boca Raton, 335-340. - References

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Barel, A.O., Courage, W. and Clarys, P. (1995) Suction method for measurement of skin mechanical properties: The Cutometer. In: Serup, J. and Jemec, G.B.E. Eds., Handbook of Noninvasive Methods and the Skin, CRC Press, Boca Raton, 335-340.

has been cited by the following article:

TITLE: Tolerability and hydrating effects of an anti-aging gynaecological collagen cream in women in menopause

AUTHORS: Andrea F. D. Di Stefano, Milko M. Radicioni, Andrea Vele, Anna Mancarella Eberhardt, Giorgio Caccia, Francesca Focanti, Enrica Salvatori

KEYWORDS: Skin Hydration; Vaginal Moisturiser; Skin Viscoelasticity; Corneometer; Cutometer; Perineum

JOURNAL NAME: Open Journal of Obstetrics and Gynecology, Vol.4 No.3, February 21, 2014

ABSTRACT: Background and Aims: A gynaecological cream containing collagen, phytocollagen, hyaluronate and vitamins was investigated in women in menopause. Methods: The cream was daily applied to the vaginal mucosa and the perineal skin as well as to the abdominal skin (healthy skin used as control) for 1 week and then on alternate days for other 2 weeks. Skin hydration and viscoelasticity were measured at baseline and after 8 and 21 days by Corneometer? CM 825 and Cutometer? MPA 850, respectively. The product use comfort and the moisturising of the vaginal mucosa were evaluated by the volunteers through a questionnaire and a visual analogue scale, respectively. Results: The local tolerability was excellent for nearly all of the volunteers (90% - 95%) and according both to dermatologist’s and gynaecologist’s evaluation. Related adverse reactions had a frequency of 15% (10% vulvovaginal burning sensation and 5% vulvovaginal discomfort). The topical hydration increased both in the perineal and the abdominal skin. Hydration increase vs. baseline was more marked on day 8 than on day 21 and was significant in the abdominal skin (p-value