Perforation of the Nasal Septum and Nasal Ulcers


A case about a HIV woman with nasal ulcers is described in this paper. In every inmunodepressed patient who has mu-cosal or cutaneous ulcers, infection by leishmanial parasites needs to be ruled out, especially when ulcers have not re-gression with usual treatments. The Leishmanial nasal disease usually shows swelling and mucosal ulcers, that may progress to necrosis. Delaying in appropriate therapy might cause irreversible damage.

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Martín-Fortea, M. , Sanjoaquín-Conde, I. , Letona-Carbajo, S. , Crusells-Canales, M. , Cuesta-Muñoz, J. and Amiguet-García, J. (2011) Perforation of the Nasal Septum and Nasal Ulcers. World Journal of AIDS, 1, 28-30. doi: 10.4236/wja.2011.12005.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] M. M. Lessa, H. A. Lessa, T. W. Castro, A. Oliveira, A. Scherifer, et al., “Mucosal Leishmaniasis: Epidemo- logical and Clinical Aspects,” Revista Brasileira de Otorrinolaringologia, Vol. 73, No. 6, 2007, pp. 843-847. doi:10.1590/S0034-72992007000600016
[2] E. Shwart, C. Hatz and J. Blum, “New World Cutaneous Leishmaniasis in Travellers,” Lancet Infectious Diseases, Vol. 6, No. 6, 2006, pp. 342-349. doi:10.1016/S1473-3099(06)70492-3
[3] M. Mateo, I. Cruz, M. D. Flores and R. López-Vélez, “Slowly Progressing Skin Ulcers Following a Stay in Costa Rica,” Enfermedades Infecciosas y Microbiología Clínica, Vol. 23, No. 4, 2005, pp. 243-244. doi:10.1157/13073152
[4] B. Herwaldt, “Leishmaniasis,” Lancet, Vol. 354, 1999, pp. 1191-1199. doi:10.1016/S0140-6736(98)10178-2
[5] J. Alvar, J. A. Ballesteros, R. Soler, A. Beniro, G. J. van Eys, et al., “Mucocutaneous Leishmaniasis due to Leishmania (Leishmania) Infantum: Biochemical Characterization,” The American Journal of Tropical Medicine and Hygiene, Vol. 43, No. 6, 1990, pp. 614-618.
[6] P. A. van Damme, M. Keuter, S. Van Assen, P. M. De-Wilde and P. J. A. Beckers, “A Rare Case of Oral Leishmaniasis,” Lancet Infectious Diseases, Vol. 4, No. 1, 2004, p. 53. doi:10.1016/S1473-3099(03)00861-2
[7] J. M. Ramos, Z. Zubero and J. Ena, “Inmigración y VIH. Aproximación a las Enfermedades Parasitarias y Vira- les,”Enfermedades Infecciosas y Microbiología Clínica, Vol. 26, No. 3, 2008, pp. 42-53. doi:10.1157/13123266
[8] M. Gallego and C. Riera, “Las Leishmaniasis Humanas. Control de Calidad de la Sociedad Espa?ola de Enfer- medades Infecciosas y Microbiología Clínica.” Consulted in June 6th, 2010.
[9] M. Trimarchi, G. Gregorini, F. Facchetti, M. L. Morassi, C. Manfredini, R. Maroldi, et al., “Cocaine-Induced Midline Destructive Lesions: Clinical, Radiographic, Histopathologic, and Serologic Features and Their Differentiation from Wegener Granulomatosis,” Medicine, Vol. 80, No. 6, 2001, pp. 391-404. doi:10.1097/00005792-200111000-00005
[10] C. B. Bonner and I. Y. Castillo, “Lesión Destructiva de la Línea Media Inducida por Cocaína: Comunicación de un Caso,” Anales de Otorrinolaringología Mexicana, Vol. 54, No. 1, 2009, pp. 32-35.
[11] Centers for Disease Control & Prevention, “National Center for Infectious Diseases, Division of Parasitic Diseases,” Consulted in 19 September 2010.
[12] J. Alvar, C. Ca?avete, B. Gutiérrez-Solar, M. Jiménez, F. Laguna, et al., “Leishmania and Human Immunodeficiency Vírus Coinfection: The Firts 10 Years,” Clinical Microbiology Reviews, Vol. 10, No. 2, 1997, pp. 298-319.
[13] M. Ara, C. Mailo, G. Peon, A. Clavel, J. Cuesta, et al., “Visceral Leishmaniasis with Cutaneous Lesions in a Patient Infected with Human Immunodeficiency Virus,” The British Journal of Dermatology, Vol. 139, No. 1, 1998, pp. 114-117. doi:10.1046/j.1365-2133.1998.02326.x

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