Synthesis of P(NIPAM-co-Am)/Mesoporous Silica Composites and Their Temperature- Responsive Anion Exchange

DOI: 10.4236/msce.2015.37002   PDF   HTML   XML   3,093 Downloads   3,676 Views   Citations


The purpose of this study is to examine the structure and the temperature-responsive anion exchange property of amino-functionalized mesoporous silica coated with temperature-responsive copolymer, poly(N-isopropylacrylamide-co-acrylamide) (P(NIPAM-co-Am)). For this purpose, the composites which contained 0, 10, or 20 wt% of Am were synthesized. From the TG results, it was found that the amounts of copolymer immobilized on the mesoporous silica were 1.6 - 2.6 wt%. XRD patterns revealed that the structures of composites were hexagonal and almost the same as that of original mesoporous silica without polymer. At low temperature the methyl orange (MO) anions adsorbed and desorbed reversibly with changing pH of the solution, while at high temperature the MO anions did not. This temperature, at which the amount of adsorbed MO anions changed considerably, shifted to the higher temperature side with increasing the amount of added Am.

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Murakami, K. , Sato, Y. and Inoue, Y. (2015) Synthesis of P(NIPAM-co-Am)/Mesoporous Silica Composites and Their Temperature- Responsive Anion Exchange. Journal of Materials Science and Chemical Engineering, 3, 7-15. doi: 10.4236/msce.2015.37002.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Xu, W., Gao, Q., Xu, Y., Wu, D. and Sun, Y. (2009) pH-Controlled Drug Release from Mesoporous Silica Tablets Coated with Hydroxypropyl Methylcellulose Phthalate. Materials Research Bulletin, 44, 606-612.
[2] Kim, H-J., Matsuda, H., Zhou, H. and Honma, I. (2006) Ultrasound-Triggered Smart Drug Release from a Poly(Dime- thylsiloxane)-Mesoporous Silica Composite. Advanced Materials, 18, 3083-3088.
[3] Mal, N.K., Fujiwara, M. and Tanaka, Y. (2003) Photocontrolled Reversible Release of Guest Molecules from Coumarin-Modified Mesoporous Silica. Nature, 421, 350-353.
[4] Rama Rao, G.V., Krug, M.E., Balamurugan, S., Xu, H., Xu, Q. and Lopez, G.P. (2002) Synthesis and Characterization of Silica-Poly(N-Isopropylacrylamide) Hybrid Membranes: Switchable Molecular Filters. Chemistry of Materials, 14, 5075-5080.
[5] Fu, Q., Rama Rao, G.V., Ista, L.K., Wu, Y., Andrzejewski, B.P., Sklar, L.A., Ward, T.L. and Lopez, G.P. (2003) Control of Molecular Transport through Stimuli-Responsive Ordered Mesoporous Materials. Advanced Materials, 15, 1262-1266.
[6] Fu, Q., Rama Rao, G.V., Ward, T.L., Lu, Y. and Lopez, G.P. (2007) Thermoresponsive Transport through Ordered Mesoporous Silica/PNIPAAm Copolymer Membranes and Microspheres. Langmuir, 23, 170-174.
[7] Tian, B.-S. and Yang, C. (2009) Temperature-Responsive Nanocomposites Based on Mesoporous SBA-15 Silica and PNIPAAm: Synthesis and Characterization. Journal of Physical Chemistry C, 113, 4925-4931.
[8] Wen, H., Guo, J., Chang, B. and Yang, W. (2013) pH-Responsive Composite Microspheres Based on Magnetic Mesoporous Silica Nanoparticle for Drug Delivery. European Journal of Pharmaceutics and Biopharmaceutics, 84, 91-98.
[9] Yu, F., Tang, X. and Pei, M. (2013) Facile Synthesis of PDMAEMA-Coated Hollow Mesoporous Silica Nanoparticles and Their pH-Responsive Controlled Release. Microporous and Mesoporous Materials, 173, 64-69.
[10] Zhao, Q., Wang, C., Liu, Y., Wang, J., Gao, Y., Zhang, X., Jiang, T. and Wang, S. (2014) PEGylated Mesoporous Silica as a Redox-Responsive Drug Delivery System for Loading Thiol-Containing Drugs. International Journal of Pharmaceutics, 477, 613-622.
[11] Wang, Y., Han, N., Zhao, Q., Bai, L., Li, J., Jiang, T. and Wang, S. (2015) Redox-Responsive Mesoporous Silica as Carriers for Controlled Drug Delivery: A Comparative Study Based on Silica and PEG Gatekeepers. European Journal of Pharmaceutical Sciences, 72, 12-20.
[12] Murakami, K., Yu, X., Watanabe, S., Kato, T., Inoue, Y. and Sugawara, K. (2011) Synthesis of Thermosensitive Polymer/Mesoporous Silica Composite and Its Temperature Dependence of Anion Exchange Property. Journal of Colloid and Interface Science, 354, 771-776.
[13] Murakami, K., Yu, X., Kato, T., Inoue, Y. and Sugawara, K. (2012) Synthesis of Temperature-Responsive Anion Exchanger via Click Reaction. Journal of Colloid and Interface Science, 376, 189-195.
[14] Murakami, K., Watanabe, S., Kato, T. and Sugawara, K. (2013) Transition Temperature Control of Adsorption-De- sorption Property of PNIPAM/Mesoporous Silica Composite by Addition of Crosslinking Agent. Colloid and Surfaces A, 419, 223-227.
[15] Murakami, K., Kato, T. and Sugawara, K. (2013) Influence of Amount of Thermosensitive Polymer on Anion-Ex- change Properties of Thermosensitive Polymer/Mesoporous Silica Composite. Kagakukogaku Ronbunshu, 39, 206-212.
[16] Wu, D., Liu, X., Yu, S., Liu, M. and Gao, C. (2010) Modification of Aromatic Polyamide Thin-Film Composite Reverse Osmosis Membranes by Surface Coating of Thermo-Responsive Copolymers P(NIPAM-co-Am). I: Preparation and Characterization. Journal of Membrane Science, 352, 76-85.
[17] Grun, M., Unger, K.K., Matsumoto, A. and Tsutsumi, K. (1999) Novel Pathways for the Preparation of Mesoporous MCM-41 Materials: Control of Porosity and Morphology. Microporous and Mesoporous Materials, 27, 207-216.
[18] Jaroniec, M., Kruk, M., Shin, H.J., Ryoo, R., Sakamoto, Y. and Terasaki, O. (2001) Comprehensive Characterization of Highly Ordered MCM-41 Silicas Using Nitrogen Adsorption, Thermogravimetry, X-Ray Diffraction and Transmission Electron Microscopy. Microporous and Mesoporous Materials, 48, 127-134.
[19] Murakami, K., Fuda, K. and Sugai, M. (2007) Geometrical Study on Change of Pore Volume of MCM-41 Functionalized with Aminopropyl Groups. Materials Research Society Symposium Proceedings, 1056.

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