Author(s)

Richell Bastos Vale¹, Bruno Vítor Martins Santiago^2*, José Abel de Almeida Neto¹, Luiz Otávio Ribeiro de Lemos Felgueiras³, Karine Grillo de Freitas³, Thiago dos Santos Ferreira^1,3

¹Department of Anesthesiology, Piedade Municipal Hospital, Rio de Janeiro, Brazil.
²Department of Anesthesiology, Marcílio Dias Naval Hospital, Rio de Janeiro, Brazil.
³Interleague Association of Anesthesiology of the State of Rio de Janeiro, Rio de Janeiro, Brazil.

The study seeks to report the clinical evolution of a patient who suffered an inadvertent subarachnoid puncture and evolved with a herpetic viral meningitis, confirmed by cerebrospinal fluid (CSF) analysis. Female, 48 years old, submitted to epidural anesthesia, for surgery, with median puncture, between L2-L3 and inadvertently accessed the subarachnoid space, with clear cerebrospinal fluid. The same puncture was used and the solution with 15 mg hyperbaric bupivacaine and 80 mcg morphine was administered. There was no complication during the entire surgical procedure. On the first postoperative day, she started complaining of headache and nausea, being treated with dipyrone, non-steroidal anti-inflammatory drugs (NSAIDs) and ondansetron. On the third day, she presented two episodes of seizure that ceased with the use of diazepam 10 mg. On the fifth day, the patient presented fever and seizures, which did not stop with medication, requiring sedation, orotracheal intubation and transfer to the intensive care unit. Lumbar puncture was performed for CSF analysis, which was positive for Herpes simplex type I. The patient was extubated, on the second day of hospitalization, maintained with a maintenance dose of phenytoin, sumatriptan, dipyrone, metoclopramide and acyclovir 500 mg, remaining intravenous, without presenting new seizures for 45 days, when she was discharged. After 30 days, he returned for a review consultation without making a complaint.

Headache, Opioids, Herpes Simplex, Dural Puncture

Vale, R. , Santiago, B. , de Almeida Neto, J. , de Lemos Felgueiras, L. , de Freitas, K. and dos Santos Ferreira, T. (2021) An Unusual Case of Herpes Simplex Meningitis after Inadvertent Puncture of the Subarachnoid Space. Case Reports in Clinical Medicine, 10, 232-239. doi: 10.4236/crcm.2021.109030.