Author(s)

Taasilkan Zhumabaeva¹, Zoya Kuropteva², Zhoomart Moldaliev¹, Nazgul Zhumabaeva³, Amanai Kadyrbaeva⁴, Nurbek Bopoev⁵, Zhypargul Abdullaeva^6*

¹Department of Natural Sciences, Osh State University, Osh, Kyrgyzstan.
²Institute of Biochemical Physics, Russian Academy of Sciences, Moscow, Russia.
³Department of Medicine, Kyrgyz-Turkish University Manas, Bishkek, Kyrgyzstan.
⁴Department of Hospital Therapy, Zhalal-Abad State University, Zhalal-Abad, Kyrgyzstan.
⁵International Hope School Bangladesh of Gulshan Branch, Dhaka, Bangladesh.
⁶Science and Research Department, Osh State University, Osh, Kyrgyzstan.

This work is investigating Mexidol (2-ethyl-6-methyl-3-hydroxy pyridine succinate) effect on the formation of nitric oxide (NO) in animal liver tissues, which is a regulator of many physiological processes and plays an important role in the vascular relaxation, neurotransmission and immune system functioning. Analyses performed by EPR spectroscopy revealed Hem-NO complex signals from paramagnetic centers in arbitrary units; produced nitrogen oxide amount in liver tissues was determined by method of double integration signals from nitrosyl complexes.

Nitroglycerine, Liver Tissue, Nitric Oxide, Mexidol, Joint Effect, EPR Spectra

Zhumabaeva, T. , Kuropteva, Z. , Moldaliev, Z. , Zhumabaeva, N. , Kadyrbaeva, A. , Bopoev, N. and Abdullaeva, Z. (2021) Joint Effects of Mexidol and Nitroglycerine on Nitric Oxide Formation in Animal Liver Tissues. American Journal of Molecular Biology, 11, 73-82. doi: 10.4236/ajmb.2021.113007.