[1]
|
[1] D. R. Nelson, L. Koymans, T. Kamataki, J. J. Stegeman, R. Feyereisen, D. J. Waxman, M. R. Waterman, O. Gotoh, M. J. Coon, R. W. Estabrook, I. C. Gunsalus and D. W. Nebert, “P450 Superfamily: Update on New Sequences, Gene Mapping, Ac-cession Numbers and Nomenclature,” Pharmacogenetics, Vol. 6, 1996, pp. 1-42. doi:10.1097/00008571-199602000-00002
|
[2]
|
[2] S. A. Kliewer, J. M. Lehmann and T. M. Willson, “Orphan Nu-clear Receptors: Shifting Endocrinology into Reverse,” Science, Vol. 284, 1999, pp. 757-760. doi:10.1126/science.284.5415.757
|
[3]
|
[3] E. L. Michalets, “Update: Clinically Significant Cyto-Chrome P-450 Drug Interactions,” Pharmacotherapy, Vol. 18, 1998, pp. 84-112.
|
[4]
|
[4] F. P. Guengerich, in: P. R. Ortiz de Montellano (Eds.), “Cyto-Chrome P450: Structure, Mechanism and Biochemistry,” Ple-num Publishers, 2005, pp. 377-425.
|
[5]
|
[5] J. Zhang, P. Kuehl, E. D. Green, J. W. Touchman, P. B. Wat-kins, A. Daly, S. D. Hall, P. Maurel, M. Relling, C. Brimer, K. Yasuda, S. A. Wrighton, M. Hancock, R. B. Kim, S. Strom, K. Thummel, C. G. Russell, J. R. Hudson, Jr., E. G. Schuetz and M. S. Boguski, “The Human Pregnane X Receptor: Genomic Structure and Identification and Functional Characterization of Natural Allelic Variants,” Pharmacogenetics, Vol. 11, 2001, pp. 555-572. doi:10.1097/00008571-200110000-00003
|
[6]
|
[6] S. A. Kliewer, J. T. Moore, L. Wade, J. L. Staudinger, M. A. Watson, S. A. Jones, D. D. McKee, B. B. Oliver, T. M. Will-son, R. H. Zetterstr?m, T. Perlmann and J. M. Lehmann, “An Orphan Nuclear Receptor Activated by Pregnanes Defines a Novel Steroid Signaling Pathway,” Cell, 92, 1998, pp. 73-82. doi:10.1016/S0092-8674(00)80900-9
|
[7]
|
[7] B. Blumberg, W. Sabbagh, Jr., H. Juguilon, J. Bolado, Jr., C. M. van Meter, E. S. Ong and R. M. Evans, “SXR, a Novel Steroid and Xenobiotic-Sensing Nuclear Receptor,” Genes and Development, Vol. 12, 1998, pp. 3195-3205.
doi:10.1101/gad.12.20.3195
|
[8]
|
[8] G. Bertilsson, J. Heidrich, K. Svensson, M. ?sman, L. Jende-berg, M. Sydow-B?ckman, R. Ohlsson, H. Postlind, P. Blom-quist and A. Berkenstam, “Identification of a Human Nuclear Receptor Defines a New Signaling Pathway for Cyp3a Induc-tion,” Proceedings of the National Academy of Sciences, Vol. 95, 1998, pp. 12208-12213. doi:10.1073/pnas.95.21.12208
|
[9]
|
[9] R. E. Watkins, G. B. Wisely, L. B. Moore, J. L. Collins, M. H. Lambert, S. P. Williams, T. M. Willson, S. A. Kliewer and M. R. Redinbo, “The Human Nuclear Xenobiotic Receptor PXR: Structural Determinants of Directed Promiscuity,” Science, Vol. 292, 2001, pp. 2329-2333. doi:10.1126/science.1060762
|
[10]
|
[10] L. B. Moore, J. M. Maglich, D. D. McKee, B. Wisely, T. M. Willson, S. A. Kliewer, M. H. Lambert and J. T. Moore, “Pregnane X Receptor (PXR), Constitutive Androstane Re-ceptor (CAR) and Benzoate X Receptor (BXR) Define Three Pharmacologically Distinct Classes of Nuclear Receptors,” Molecular Endocrinology, Vol. 16, 2002, pp. 977-986.
doi:10.1210/me.16.5.977
|
[11]
|
[11] C. Zhou, S. Verma and B. Blumberg, “The Steroid and Xeno-biotic Receptor (Sxr), Beyond Xenobiotic Metabolism,” Nu-clear Receptor Signaling, Vol. 7, 2009, pp. 1-21.
|
[12]
|
[12] S. A. Kliewer, B. Goodwin and T. M. Willson, “The Nuclear Pregnane X Receptor: A Key Regulator of Xenobiotic Me-tabolism,” Endocrine Reviews, Vol. 23, 2002, pp. 687-702. doi:10.1210/er.2001-0038
|
[13]
|
[13] J. E. Chrencik, J. Orans, L. B. Moore, Y. Xue, L. Peng, J. L. Collins, G. B. Wisely, M. H. Lambert, S. A. Kliewer and M. R. Redinbo, “Structural Disorder in the Complex of Human Pregnane X Receptor and the Macrolide Antibiotic Rifam-picin,” Molecular Endocrinology, Vol. 19, 2005, pp. 1125- 1134. doi:10.1210/me.2004-0346
|
[14]
|
[14] J. T. Moore and S. A. Kliewer, ‘Use of the Nuclear Recaptor Pxr to Predict Drug Interactions,” Toxicology, Vol. 153, 2000, pp. 1-10. doi:10.1016/S0300-483X(00)00300-0
|
[15]
|
[15] P. Dutta, K. Hill, P. G. Datskos and M. J. Sepaniak, “Devel-opment of a Nanomechanical Biosensor for Analysis of Endo-crine Disrupting Chemicals,” Lab Chip, Vol. 7, 2007, pp. 1184-1191. doi:10.1039/b704723a
|
[16]
|
[16] K. Hill, P. Dutta, A. Zareba, M. L. Eldridge and M. J. Sepaniak, “Morphological and Chemical Optimization of Microcantile-ver Surfaces for Thyroid System Sensing and Beyond,” Ana-lytica Chimica Acta, Vol. 625, 2008, pp. 55-62.
doi:10.1016/j.aca.2008.07.005
|
[17]
|
[17] C. A. Tipple, N. V. Lavrik, M. Culha, J. Headrick, P. Datskos and M. J. Sepaniak, “Nanostructured Microcantilevers with Functionalized Cyclodextrin Receptor Phases: Self Assembled Monolayers and Vapor Deposited Films,” Analytical Chemis-try, Vol. 74, 2002, pp. 3118-3126. doi:10.1021/ac020074o
|
[18]
|
[18] P. Dutta, P. J. Chapman, P. G. Datskos and M. J. Sepaniak, “Characterization of Ligand-Functionalized Microcantilevers for Metal Ion Sensing,” Analytical Chemistry, Vol. 77, 2005, pp. 6601-6608. doi:10.1021/ac051082i
|
[19]
|
[19] P. Dutta, J. Sanseverino, P. G. Datskos and M. J. Sepaniak, “Detection of Cytokine Using a Microcantilever Biosensor,” NanoBiotechnology, 1, 2005, pp. 237-244.
doi:10.1385/NBT:1:3:237
|
[20]
|
[20] R. Berger, E. Delamarche, H. P. Lang, C. Gerber, J. K. Gim-zewski, E. Meyer and H. J. Guntherodt, “Surface Stress in the Self-Assembly of Alkanethiols on Gold,” Science, Vol. 276, 1997, pp. 2021-2024. doi:10.1126/science.276.5321.2021
|
[21]
|
[21] T. Thundat, E. A. Wachter, S. L. Sharp and R. J. Warmack, “Detection of Mercury Vapor Using Resonating Microcanti-levers,” Applied Physics Letters, Vol. 66, 1995, pp. 1695-1697. doi:10.1063/1.113896
|
[22]
|
[22] P. Dutta, C. A. Tipple, N. V. Lavrik, P. G. Datskos, O. Hof-stetter and M. J. Sepaniak, “Enantioselective Sensors Based on Antibody Mediated Nanomechanics,” Analytical Chemistry, Vol. 75, 2003, pp. 2342-2348. doi:10.1021/ac034031z
|
[23]
|
[23] G. Wu, R. H. Datar, K. M. Hansen, T. Thundat, R. J. Cote and A. Majumdar, “Bioassay of Prostate-Specific Antigen (Psa) Using Microcantilevers,” National Biotechnology, Vol. 19, 2001, pp. 856-860. doi:10.1038/nbt0901-856
|
[24]
|
[24] C. Grogan, R. Raiteri, G. M. O’Connor, T. J. Glynn, V. Cun-ningham, M. Kane, M. Charlton and D. Leech, “Characteriza-tion of an Antibody Coated Microcantilever as a Potential Immuno-Based Biosensor,” Biosensor Bioelectronics, Vol. 17, 2002, pp. 201-207. doi:10.1016/S0956-5663(01)00276-7
|
[25]
|
[25] J. Fritz, M. K. Baller, H. P. Lang, H. Rothuizen, P. Vettiger, E. Meyer, H. Guntherodt, C. Gerber and J. K. Gimzewski, “Translating Biomolecular Recognition into Nanomechanics,” Science, Vol. 288, 2000, pp. 316-318.
doi:10.1126/science.288.5464.316
|
[26]
|
[26] G. Shekhawat, S. H. Tark and V. P. Dravid, “MOS-FET-Embedded Microcantilevers for Measuring Deflection in Biomolecular Sensors,” Science, Vol. 311, 2006, pp. 1592- 1595. doi:10.1126/science.1122588
|
[27]
|
[27] S. A. Jones, L. B. Moore, J. L. Shenk, G. B. Wisely, G. A. Hamilton, .D. D. McKee, N. C. O. Tomkinson, E. L. LeCluyse, M. H. Lambert, T. M. Willson, S. A. Kliewer and J. T. Moore, “The Pregnane X Receptor: A Promis-Cuous Xenobiotic Re-ceptor That Has Diverged during Evolution,” Molecular En-docrinology, Vol. 14, 2000, pp. 27-39. doi:10.1210/me.14.1.27
|
[28]
|
[28] S. J. Shukla, D. Nguyen, R. MacArthur, A. Simeonov, W. J. Frazee, T. M. Hallis, B. D. Marks, U. Singh, H. C. Eliason, J. Printen, C. P. Austin, J. Inglese and D. S. Auld, “Identification of Pregnane X Receptor Ligands Using Time-Resolved Fluo-rescence Resonance Energy Transfer and Quantitative High- Throughput Screening,” Assay and Drug Development Tech-nologies, Vol. 7, 2009, pp. 143-169.
doi:10.1089/adt.2009.193
|
[29]
|
[29] G. G. Stoney, “The Tension of Metallic Films Deposited by Electrolysis,” Proceeding of the Royal Society of London, Se-rial A, Vol.82, 1909, pp. 172-177.
|
[30]
|
[30] T. S. Kim, D. S. Yoon and J. H. Lee, in: N. P. Mahalik, Ed. “Micromanufacturing and Nanotechnology,” Springer, Berlin, 2006, pp. 299-321.
|
[31]
|
[31] N. V. Lavrik, C. A. Tipple, M. J. Sepaniak and P. G. Datskos, “Enhanced Chemi-Mechanical Transduction at Nanostructured Interfaces,” Chemical Physics Letters, Vol. 336, 2001, pp. 371-376. doi:10.1016/S0009-2614(01)00155-5
|
[32]
|
[32] J. R. Premkumar, O. Lev, R. S. Marks, B. Polyak, R. Rosen and S. Belkin, “Antibody-based Immobilization Of Biolumi-nescent Bacterial Sensor Cells,” Talanta, Vol. 55, 2001, pp. 1029-1038. doi:10.1016/S0039-9140(01)00533-1
|
[33]
|
[33] S. W. Park, Y. I. Kim, K. H. Chung, S. I. Hong and S. W. Kim, “Covalent Immobilization of Gl-7-Aca Acylase on Silica Gel Through Silanization,” Reactive Functional Polymers, Vol. 51, 2002, pp. 79-92. doi:10.1016/S1381-5148(02)00028-7
|
[34]
|
[34] P. J. Chapman, Z. Long, P. G. Datskos, R. Archibald and M. J. Sepaniak, “Ligand-Functionalized Microcantilever Arrays for Metal Ion Sensing,” Analytical Chemistry, Vol. 79, 2007, pp. 7062-7068. doi:10.1021/ac070754x
|
[35]
|
[35] L.R. Senesac, P. Dutta, P. G. Datskos and M.J. Sepaniak, “Analyte Identification Using Differentially-Functionalized Microcantilever Arrays and Artificial Neural Nets,” Analytical Chemistry Acta, Vol. 558, 2006, pp. 94-101.
doi:10.1016/j.aca.2005.11.024
|
[36]
|
[36] P.J. Chapman, Z. Long, P.G. Datskos, R. Archbald and M.J. Sepaniak, “Ligand-Functionalized Microcantilever Arrays for Metal Ion Sensing” Analytical Chemistry, Vol. 79, 2007, pp. 7062-7068. doi:10.1021/ac070754x
|
[37]
|
[37] Z. Long, John Story, Samuel Lewis and M.J. Sepaniak “Land-fill Siloxane Gas Sensing Using Differentiating, Responsive Phase Coated Microcantilever Arrays” Analytical Chemistry, Vol. 81, 2009, pp. 2575-2580. doi:10.1021/ac802494v
|
[38]
|
[38] M. J. Sepaniak, P. G. Datskos, N. V. Lavrik and C. Tipple, “Microcantilever Transducers: A New Approach in Sensor Technology,” Analytical Chemistry, 2002, 568A-575A.
|
[39]
|
[39] J. L. Staudinger, B. Goodwin, S. A. Jones, D. Hawkins-Brown, K. I. MacKenzie, A. LaTour, Y. Liu, C. D. Klaassen, K. K. Brown, J. Reinhard, T. M. Willson, B. H. Koller and S. A. Kliewer, “The Nuclear Receptor PXR is a Lithocholic Acid Sensor That Protects against Liver Toxicity,” Processings of the National Academy Sciences, Vol. 98, 2001, pp. 3369-3374. doi:10.1073/pnas.051551698
|
[40]
|
[40] E. Y. H. Yeung, T. Sueyoshi, M. Negishi and T. K. H. Chang, “Identification of Ginkgo Biloba as a Novel Activator of Pregnane X Receptor,” Drug Metabolism and Disposition, Vol. 36, 2008, pp. 2270-2276. doi:10.1124/dmd.108.023499
|
[41]
|
[41] S. Kortagere, D. Chekmarev, W. J. Welsh and S. Ekins, “Hy-brid Scoring and Classification Approaches to Predict Human Pregnane X Receptor Activators,” Pharmaceutical Research, Vol. 26, 2009, pp. 1001-1011.
doi:10.1007/s11095-008-9809-7
|
[42]
|
[42] P. Li, “Evaluation of Luciferin-Isopropyl Acetal as a CYP3A4 Substrate for Human Hepatocytes: Effects of Organics Sol-vents, Cytochrome P450 (P450) Inhibitors and P450 Induc-ers,” Drug Metabolism and Disposition, Vol. 37, 2009, pp. 1598-1603. doi:10.1124/dmd.109.027268
|
[43]
|
[43] M. Abdelrahim, E. Ariazi, K. Kim, S. Khan, R. Barhoumi, R. Burghardt, S. Liu, D. Hill, R. Finnell, B. Wlodarczyk, V. C. Jordan and S. Safe, “3-Methylcholanthrene and Other Aryl Hydrocarbon Receptor Agonists Directly Activate Estrogen Receptor,” Cancer Research, Vol. 66, 2006, pp. 2459-2467. doi:10.1158/0008-5472.CAN-05-3132
|
[44]
|
[44] J. P. Jackson, K. K. Kabirov, I. M. Kapetanovic and A. Lyu-bimov, “In Vitro Assessment of p450 Induction Potential of Novel Chemopreventive Agents sr13668, 9-cis-uab30 and Pentamethychromanol In Primary Cultures of Human Hepa-tocytes,” Chemical-Biology Interactive, Vol. 179, 2009, pp. 263-272. doi:10.1016/j.cbi.2008.12.005
|
[45]
|
[45] H. Kuramitz, J. Natsui, K. Sugawara, S. Itoh and S. Tanaka, “Electrochemical Evaluation of the Interaction between Endo-crine Disruptor Chemicals and Estrogen Receptor Using 17-Estradiol Labeled with Daunomycin,” Analytical Chemistry, Vol. 74, 2002, pp. 533-538. doi:10.1021/ac010426b
|
[46]
|
[46] G. G. J. M. Kuiper, J. G. Lemmen, B. Carlson, J. C. Corton, S. H. Safe, P. T. Van Der Saag, B. Van Der Burg and J. Gustafs-son, “Interaction of Estrogenic Chemicals and Phytoestrogens with Estrogen Receptor,” Endocrinology, Vol. 139, 1998, pp. 4252-4263. doi:10.1210/en.139.10.4252
|
[47]
|
[47] S. Stoica, B. S. Katzenellenbogen and M. B. Martin, “Activa-tion of Estrogen Receptor—by the Heavy Metal Cadmium,” Molecular Endocrinology, Vol. 14, 2000, pp. 545-553.
doi:10.1210/me.14.4.545
|
[48]
|
[48] D. J. Mangelsdorf, C. Thummel, M. Besto, P. Herrlich, G. Schütz, K. Umesono, B. Blumberg, P. Kastner, M. Mark, P. Chambon and R. M. Evans, “The Nuclear Receptor Super-family: The Second Decade,” Cell, Vol. 83, 1995, pp. 835-839. doi:10.1016/0092-8674(95)90199-X
|
[49]
|
[49] H. Masuyama, Y. Hiramatsu, M. Kunitomi, T. Kudo and P. N. MacDonald, “Endocrine Disrupting Chemicals, Phthalic Acid and Nonylphenol, Activate Pregnane X Receptor-Mediated Transcription,” Molecular Endocrinology, Vol. 14, 2000, pp. 421-428. doi:10.1210/me.14.3.421
|
[50]
|
[50] H. Masuyama, N. Suwaki, Y. Tateishi, H. Nakatsukasa, T. Seqawa and Y. Hiramatsu, “The Pregnane X Receptor Regu-lates Gene Expression in a Ligand and Promoter-Selective Fashion,” Molecular Endocrinology, Vol. 19, 2005, pp. 1170- 1180. doi:10.1210/me.2004-0434
|
[51]
|
[51] D. Hopwood, C. R. Allen and M. McCabe, “The Reactions between Glutaraldehyde and Various Protein. An Investigation of Their Kinetics,” Histochemical Journal, Vol. 2, 1970,
pp. 137-150. doi:10.1007/BF01003541
|
[52]
|
[52] D. R. Walt and V. I. Agayn, “The Chemistry of Enzyme and Protein Immobilization with Glutaraldehyde,” Trends Analyti-cal Chemistry, Vol. 13, 1994, pp. 425-430.
doi:10.1016/0165-9936(94)85023-2
|