Helicobacter pylori is the main cause of gastrointestinal dis- orders, particularly pepticulcer, chronic gastritis, gastricadeno-carcinoma and mucosa-associated lymphoid tissue (MALT) lym- phoma [1] . The prevalence of infection with H. pylori in Iran varies from 36% in Kurdistan to 90% in Ardabil [2] . Depending on resistance to clarithromycin, combined treatment regimens have been introduced in three categories as follows: (i) first-line therapy, comprising a proton pump inhibitor (PPI) plus two antibiotics such as amoxicillin and clarithromycin (in areas with low clarithromycin resistance); (ii) bismuth quadruple therapy, com- prising a PPI plus bismuth salt, tetracycline and metronidazole (in areas with high clarithromycin resistance); and (iii) non-bismuth quadruple therapy, comprising one PPI plus three antibiotics such as clarithromycin, amoxicillin, and metronidazole or tinidazole [3–5] . Nowadays, increasing antibiotic resistance as well as degrada- tion of antibiotics in the stomach are considered two major obstacles in eradicating H. pylori infection [3] . Excessive antibiotic resistance, especially to clarithromycin, leads to a reduction in treatment success with triple therapy regimens to ≤80% [ 6 , 7 ].
Sample Chapter(s)
Preface (2428 KB)
Components of the Book:
- Chapter 1
Levofloxacin-based therapy as an efficient alternative for eradicating Helicobacter pylori infection in Iran a systematic review and meta-analysis
- Chapter 2
Association of Helicobacter pylori infection with estimated glomerular filtration rate in a Chinese population
- Chapter 3
The role of the occupational physician in controlling gastric cancer attributable to Helicobacter pylori infection A review
- Chapter 4
Helicobacter pylori and its association with autoimmune diseases systemic lupus erythematosus, rheumatoid arthritis and Sjögren syndrome
- chapter 5
Evaluating the relationship between Helicobacter pylori infection and carotid intima-media thickness a cross sectional study
- chapter 6
Lower Incidence of Hepatobiliary Cancer in Helicobacter pylori-Infected Persons A Cohort Study of 53.633 Persons
- Chapter 7
Association between Helicobacter pylori infection and carotid atherosclerosis in Chinese adults
- Chapter 8
Ecological models of gastric microbiota dysbiosis Helicobacter pylori and gastric carcinogenesis
- Chapter 9
Cellular evasion strategies of Helicobacter pylori in regulating its intracellular fate
- Chapter 10
Geographically Distinct North-East Indian Helicobacter pylori Strains are Highly Sensitive to Clarithromycin but are Levofloxacin Resistant
- Chapter 11
Diagnosis and treatment of Helicobacter pylori infections in children and elderly populations
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Chapter 1 Levofloxacin-based therapy as an efficient alternative for eradicating Helicobacter pylori infection in Iran a systematic review and meta-analysis
Masoud Keikha a , b , 1 , Parvin Askari c , 1 , Kiarash Ghazvini a , b , Mohsen Karbalaei
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Chapter 2 Association of Helicobacter pylori infection with estimated glomerular filtration rate in a Chinese population
Xueying Wang a,b,1, Zhifang Jia a,1, Yangyu Zhang a, Changgui Kou b,*, Jing Jiang a,*
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Chapter 3 The role of the occupational physician in controlling gastric cancer attributable to Helicobacter pylori infection A review
Paolo Boffetta a
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Chapter 4 Helicobacter pylori and its association with autoimmune diseases systemic lupus erythematosus, rheumatoid arthritis and Sjögren syndrome
Ivet Etchegaray-Morales a
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chapter 5 Evaluating the relationship between Helicobacter pylori infection and carotid intima-media thickness a cross sectional study
Hamid Reza Talari
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chapter 6 Lower Incidence of Hepatobiliary Cancer in Helicobacter pylori-Infected Persons A Cohort Study of 53.633 Persons
Linda S. Kornerup
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Chapter 7 Association between Helicobacter pylori infection and carotid atherosclerosis in Chinese adults
Cheng Jin
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Chapter 8 Ecological models of gastric microbiota dysbiosis Helicobacter pylori and gastric carcinogenesis
8. Ecological models of gastric microbiota dysbiosis Helicobacter pylori and gastric carcinogenesis
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Chapter 9 Cellular evasion strategies of Helicobacter pylori in regulating its intracellular fate
Wei Yang Sit
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Chapter 10 Geographically Distinct North-East Indian Helicobacter pylori Strains are Highly Sensitive to Clarithromycin but are Levofloxacin Resistant
Shweta Mahant
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Chapter 11 Diagnosis and treatment of Helicobacter pylori infections in children and elderly populations
Yi Hu
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Masoud Keikha, Antimicrobial Resistance Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Parvin Askari, Department of Microbiology, School of Medicine, Birjand University of Medical Sciences, Birjand, Iran
Kiarash Ghazvini, Department of Microbiology and Virology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Mohsen Karbalaei, Department of Microbiology and Virology, Faculty of Medicine, Jiroft University of Medical Sciences, Jiroft, Iran
Giulia Fiorini, Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy
and more...