Chemical imaging (as quantitative – chemical mapping) is the analytical capability to create a visual image of components distribution from simultaneous measurement of spectra and spatial, time information. Hyperspectral imaging measures contiguous spectral bands, as opposed to multispectral imaging which measures spaced spectral bands.
The main idea - for chemical imaging, the analyst may choose to take as many data spectrum measured at a particular chemical component in spatial location at time; this is useful for chemical identification and quantification. Alternatively, selecting an image plane at a particular data spectrum (PCA - multivariable data of wavelength, spatial location at time) can map the spatial distribution of sample components, provided that their spectral signatures are different at the selected data spectrum.
Software for chemical imaging is most specific and distinguished from chemical methods such as chemometrics.
Imaging instrumentation has three components: a radiation source to illuminate the sample, a spectrally selective element, and usually a detector array (the camera) to collect the images. The data format is called a hypercube. The data set may be visualized as a data cube, a three-dimensional block of data spanning two spatial dimensions (x and y), with a series of wavelengths (lambda) making up the third (spectral) axis. The hypercube can be visually and mathematically treated as a series of spectrally resolved images (each image plane corresponding to the image at one wavelength) or a series of spatially resolved spectra.
Components of the Book:
- Chapter 1
The utility of chemical shift imaging and related fat suppression as standalone technique in cryptorchidism using low field MRI
- Chapter 2
Analysis of minor elements in steel and chemical imaging of micro-patterned polymer by laser ablation-spark discharge-optical emission spectroscopy and laser-induced breakdown spect
- Chapter 3
DNA Microscopy Optics-free Spatio-genetic Imaging by a Stand-Alone Chemical Reaction
- Chapter 4
Chemical Heterogeneity of Deposits Formed in the Flocculant Flow From Crude Oil, According to FTIR Microscopy and Chemical Imaging
- Chapter 5
Assessment of drug content uniformity of atropine sulfate triturate by liquid chromatography–tandem mass spectrometry, X-ray powder diffraction, and Raman chemical imaging
- Chapter 6
Chemical shift MR imaging in the lumbar vertebra the effect of field strength, scanner vendors and flip angles in repeatability of signal intensity index measurement
- Chapter 7
Preliminary application of 3.0 T magnetic resonance chemical exchange saturation transfer imaging in brain metastasis of lung cancer
- Chapter 8
FDG-PET vs. chemical shift MR imaging in differentiating intertrabecular metastasis from hematopoietic bone marrow hyperplasia
- Chapter 9
Assessment of Active Pharmaceutical Ingredient Particle Size in Tablets by Raman Chemical Imaging Validated using Polystyrene Microsphere Size Standards
- Chapter 10
XEOM 1 - A novel microscopy system for the chemical imaging of heritage metal surfaces
- Chapter 11
The added value of chemical shift imaging in evaluation of bone marrow changes in sickle cell disease
- Chapter 12
The added value of chemical shift imaging in evaluation of bone marrow changes in sickle cell disease
- Chapter 13
Associations of thigh muscle fat infiltration with isometric strength measurements based on chemical shift encoding-based water-fat magnetic resonance imaging
Readership:
Students, academics, teachers and other people attending or interested in Chemical Imaging
Joshua A. Weinstein
Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA
Aviv Regev
Department of Biology, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02140, USA
A.S. Shalygina
Boreskov Institute of Catalysis, Siberian Branch of Russian Academy of Sciences, Novosibirsk, 630090 Russia
Kei Moriyama
Shujitsu University, School of Pharmacy, 1-6-1 Nishigawara, Naka-ku, Okayama 703-8516, Japan
Nozomi Oki
Department of Radiological Sciences, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan
and more...