Advances in Retinal Repair

The retina is the innermost, light-sensitive layer, or "coat", of shell tissue of the eye of most vertebrates and some molluscs. The optics of the eye create a focused two-dimensional image of the visual world on the retina, which translates that image into electrical neural impulses to the brain to create visual perception, the retina serving much the same function as film or a CCD in a camera.


In the present book, twelve typical literatures about retinal repair published on international authoritative journals were selected to introduce the worldwide newest progress, which contains reviews or original researches on Retinal-Ischemia, Retinal Laser Technology, Selective Retinal Therapy, Retinal Coordinate and Retinal Pigment Epithelium, etc. We hope this book can demonstrate advances in retinal repair as well as give references to the researchers, students and other related people.

Components of the Book:
  • Chapter 1
    Pluripotent Stem Cells for Retinal Tissue Engineering: Current Status and Future Prospects
  • Chapter 2
    Harnessing the Potential of Human Pluripotent Stem Cells and Gene Editing for the Treatment of Retinal Degeneration
  • Chapter 3
    Retinal Degeneration and Regeneration—Lessons From Fishes and Amphibians
  • Chapter 4
    Inferior retinotomy and silicone oil tamponade for recurrent inferior retinal detachment and grade C PVR in eyes previously treated with pars plana vitrectomy or scleral buckle
  • Chapter 5
    Prophylactic intravitreal 5-fluorouracil and heparin to prevent proliferative vitreoretinopathy in high-risk patients with retinal detachment: study protocol for a randomized controlled trial
  • Chapter 6
    Autophagy regulates death of retinal pigment epithelium cells in age-related macular degeneration
  • Chapter 7
    Use of bioreactors for culturing human retinal organoids improves photoreceptor yields
  • Chapter 8
    Microglia activation is essential for BMP7-mediated retinal reactive gliosis
  • Chapter 9
    The formation of a functional retinal pigment epithelium occurs on porous polytetrafluoroethylene substrates independently of the surface chemistry
  • Chapter 10
    Complementary research models and methods to study axonal regeneration in the vertebrate retinofugal system
  • Chapter 11
    Intravitreal administration of multipotent mesenchymal stromal cells triggers a cytoprotective microenvironment in the retina of diabetic mice
  • Chapter 12
    Dynamic changes in microglial and macrophage characteristics during degeneration and regeneration of the zebrafish retina
Readership: Students, academics, teachers and other people attending or interested in retinal repair study.
Ratnesh Singh, BioTime, Inc., Alameda, USA

Anastasios Georgiadis, Department of Genetics, UCL Institute of Ophthalmology, London, UK

Raffaele Mancino, Ophthalmology Unit, Department of Experimental Medicine and Surgery, University of Rome “Tor Vergata”, Rome, Italy

Friederike Schaub, Department of Ophthalmology, University of Cologne, Cologne, Germany

Daria Kraus, Clinical Trials Center Cologne (CTCC), Cologne, Germany

Moritz Felsch, Institute of Medical Statistics and Computational Biology (IMSB), University of Cologne, Cologne, Germany

and more...
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