Coronary heart disease (CHD), also known as coronary artery disease, is a group of diseases that includes: stable angina, unstable angina, myocardial infarction, and sudden cardiac death. In 2013, CHD was the most common cause of death globally, resulting in 8.14 million deaths (16.8%) up from 5.74 million deaths (12%) in 1990. The risk of death from CHD for a given age has decreased between 1980 and 2010 especially in developed countries. The number of cases of CHD for a given age has also decreased between 1990 and 2010. Since the 1990s the search for new treatment options for coronary artery disease patients, particularly for so called "no-option" coronary patients, focused on usage of angiogenesis and stem cell therapies. Numerous clinical trials were performed, either applying protein (angiogenic growth factor) therapies, such as FGF-1 or VEGF, or cell therapies using different kinds of adult stem cell populations. Research is still going on with first promising results particularly for FGF-1 and utilization of endothelial progenitor cells.

In the present book, fifteen typical literatures about coronary heart disease published on international authoritative journals were selected to introduce the worldwide newest progress, which contains reviews or original researches on medical science, aging-associated disease, heart diseases, ischemic heart disease, ect. We hope this book can demonstrate advances in coronary heart disease as well as give references to the researchers, students and other related people.