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Sreenivasan, P.K., Vered, Y., Zini, A., Mann, J., Kolog, H., Steinberg, D., Zambon, J.J., Haraszthy, V.I., da Silva, M.P. and DeVizio, W. (2011) A 6-month study of the effects of 0.3% triclosan/copolymer dentifrice on dental implants. Journal of Clinical Periodontology, 38, 33-42.
doi:10.1111/j.1600-051X.2010.01617.x
has been cited by the following article:
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TITLE:
An in vitro study of antimicrobial agents incorporated into interim restorative materials
AUTHORS:
Arely Denisse Garza Garza, Violet I. Haraszthy, Jane D. Brewer, Edward Monaco, Jennifer Kuracina, Joseph J. Zambon
KEYWORDS:
Interim Restorations; Bis-Acryl Resin; Triclosan; Cetylpyridinium Chloride
JOURNAL NAME:
Open Journal of Stomatology,
Vol.3 No.1,
March
29,
2013
ABSTRACT:
Aim: To test the hypothesis that antimicrobial agents can be incorporated into bis-acryl resin and that the material will inhibit bacterial growth in vitro. Materials and Methods: 0.5%, 1% and 2% triclosan (5-chloro-2-(2,4-dichlorophenoxy)phenol) and 0.05% 0.01% and 0.15% cetylpyridinium chloride were incorporated into bis-acryl resins and molded into 1 mm × 10 mm discs. The discs were placed on bacterial culture media inoculated with Aggregatibacter actinomycetemcomitans strain Y4, Porphyromonas gingivalis strain SUNYaB A7A1-28 or Streptococcus gordonii strain 10558, incubated and examined for growth inhibition. Results: Triclosan-containing bisacryl resin discs produced dose-dependent zones of growth inhibition for A. actinomycetemcomitans but not S. gordonii or P. gingivalis. Cetylpyridinium chloride-containing discs produced dose-dependent zones of growth inhibition for Porphyromonas gingivalis and Streptococcus gordonii but not A. actinomycetemcomitans. Conclusion: Triclosan and cetylpyridinium chloride can be incorporated into bis-acryl resin and can inhibit the growth of plaque bacteria in a dose dependent manner. Bis-acryl resin containing antimicrobial agents may inhibit in vivo plaque accumulation and gingival inflammation.
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