TITLE:
Acellular Amniotic Membrane Patch Regeneration for Burn Injury: The Future for Wound Healing
AUTHORS:
Tayná Dias, Kalyane Machado, Kátia Renata Antunes Kochla, Ricardo Cunha, Marco André Cardoso, Rossana Baggio Simeoni, Vinicius Coneglian Santos, Péricles Varella Gomes, Luiz Claudio Sobrinho do Nascimento, Maria Elisa Brum do Nascimento, Luiz Cesar Guarita-Souza, Alessandro Brawerman, Julio Cesar Francisco
KEYWORDS:
Skin Regeneration, Amniotic Membrane, Wound Healing, Tissue Engineering
JOURNAL NAME:
Journal of Biomedical Science and Engineering,
Vol.12 No.8,
August
21,
2019
ABSTRACT: Acellular amniotic membrane (AAM) is a biodegradable and biocompatible natural that has a wide range of applications in the field of pharmaceutics, biomedical, chemical and cosmetics industry. One of the most interesting characteristics of AAM is its antibacterial and anti-inflammatory, anti-angiogenic, anti-fibrosis activity is an attractive approach for treating inflammatory disorders, wounds, and burns. The isolated use of AAM may not be sufficient to produce an adequate anti-inflammatory and antimicrobial effect to fulfill different purposes, has attracted considerable attention that has similar properties to the native tissues. This mini-review offers a focuses on modern aspects of the biomaterials, growth factors, biocompatibility, and acellular matrix which are the basic elements for use in the tissue regeneration and replacement after an injury.