TITLE:
Mass Spectrometry Study of Non-Covalent Complexes of Bioflavonoids with Cyclotriveratrylene Synthesized in Subcritical Water
AUTHORS:
Anna V. Lekar, Sergey N. Borisenko, Elena V. Vetrova, Roman N. Borisenko, Nickolay I. Borisenko
KEYWORDS:
Subcritical Water; Cyclotriveratrylene (CTV); Quercetin; Dihydroquercetin; ESI Mass Spectrometry
JOURNAL NAME:
American Journal of Analytical Chemistry,
Vol.4 No.9,
September
13,
2013
ABSTRACT: Mass spectrometry was
used for studying of non-covalent complexes of bioflavonoids with cyclotriveratrylene
(CVT). The complexes of cyclotriveratrylene (CVT) with the bioflavonoids
(quercetin or dihydroquercetin) have been synthesized in subcritical water. The
complexe formation was carried out at different
temperatures of subcritical water (from 120℃ to 230℃). The structure of the inclusion compounds was confirmed by the data of ESI MS spectroscopy. The mass spectrometry results
showed the presence of mixed adducts of CTV monomer, dimer, trimer and
tetramer with quercetin and dihydroquercetin. Composition of the CTV complexes
with the bioflavonoids, which were obtained in subcritical water medium and by traditional method, was compared.