TITLE:
A Case of Type I Hepatorenal Syndrome Treated with Vasopressin
AUTHORS:
Laura Connor, Geoffrey Teehan
KEYWORDS:
Hepatorenal Syndrome; Vasopressin
JOURNAL NAME:
Open Journal of Nephrology,
Vol.3 No.3,
September
9,
2013
ABSTRACT:
Hepatorenal syndrome (HRS) is a grave complication of
end-stage liver disease and is associated with a very high mortality.
This case report described a 42-year-old female with advanced
alcohol-induced cirrhosis who developed HRS that was initially treated with
Midodrine and Octreotide but renal function continued to deteriorate.
Vasopressin therapy was added and HRS was successfully reversed. There are few data
available on the use of vasopressin for HRS and this case supports its use in
treatment of HRS, particularly in countries where the more widely studied
Terlipressin is unavailable. This case also demonstrates that a patient failing one
medical therapy for HRS may respond to an alternative or adjunctive therapy. Therefore, this
should be attempted to increase the patient’s chance of survival.