TITLE:
Xanthogranulomatous Pyelonephritis Associated with Crohn’s Disease and Primary Hyperparathyroidism
AUTHORS:
Mekdess Abebe, Wing Mu, Heesuck Suh, Edward P. Nord, Nand K. Wadhwa
KEYWORDS:
Xanthogranulomatous Pyelonephritis; Hyperparathyroidism; Crohn’s; Hypercalcemia
JOURNAL NAME:
Open Journal of Nephrology,
Vol.3 No.3,
September
9,
2013
ABSTRACT: We report on a case of unilateral and diffuse
xanthogranulomatous pyelonephritis (XGP) associated with Crohn’s disease
and primary hyperparathyroidism (HPT). The patient had undiagnosed primary HPT
for at least a year prior to presentation. The co-existence of Crohn’s disease
and primary HPT caused calcium oxalate stone likely by the known mechanism of
hypercalcemia and hyperoxaluria respectively. The patient developed XGP, a rare
disease, as a result of infected calcium oxalate stone which was treated with
antibiotics and unilateral nephrectomy. To the best of our knowledge, this is
the first case of XGP associated with Crohn’s disease and primary HPT.