TITLE:
Effect of Exercise Training Combined with Galantamine on Neurological Function and Muscle Strength Recovery in Patients with Hemiplegia after Acute Ischemic Stroke
AUTHORS:
Yuru Liang, Dongxu Liang, Longjian Huang
KEYWORDS:
Galantamine, Exercise Training, Acute Ischemic Stroke, Neurological Function Recovery, Retrospective Analysis
JOURNAL NAME:
International Journal of Clinical Medicine,
Vol.17 No.3,
March
12,
2026
ABSTRACT: Objective: To analyze the effect of exercise training combined with galantamine hydrobromide injection on the neurological and motor function of patients with hemiplegia after acute ischemic stroke. Methods: A total of 100 patients with acute ischemic stroke admitted to the Department of Neurology of our hospital from April 2025 to February 2026 were selected as the study subjects. According to the intervention protocol, they were divided into an observation group (50 cases receiving galantamine + conventional treatment + exercise training) and a control group (50 cases receiving conventional treatment + exercise training). General clinical data were collected from both groups, and assessments were performed before and after intervention using the National Institutes of Health Stroke Scale (NIHSS), Modified Rankin Scale (mRS), and Manual Muscle Test (MMT). Results: There were no statistically significant differences in gender, age, TOAST classification, or disease course between the observation group and the control group of patients with acute ischemic stroke hemiplegia (P > 0.05). Compared between the observation group and the control group, the MMT values were significantly higher after treatment than before, with statistically significant differences (P P > 0.05). After treatment, the mRS scores and NIHSS scores in both groups decreased significantly compared to pre-treatment levels (P P χ2 = 5.93, P > 0.05), whereas a statistically significant difference was noted in lower limb muscle strength efficacy (χ2 = 16.07, P P Conclusion: Galantamine combined with exercise training can promote the recovery of neurological function and muscle strength in patients with acute ischemic stroke, improve the ability of daily living activities.