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has been cited by the following article:

• TITLE: Follow-Up of HPV Clearance after LEEP Conization and Vaporization for CIN2+, and Vaporization for VaIN2

  AUTHORS: Kenji Niwa, Saki Tsurue, Rui Kyogoku, Masanori Isobe, Yoh Hayasaki, Sakae Mori, Keigo Kuwabara, Kentaro Niwa, Takuji Tanaka

  KEYWORDS: HPV, CINs, LEEP Conization, Vaporization, VaIN

  JOURNAL NAME: Open Journal of Pathology, Vol.15 No.3, July 8, 2025

  ABSTRACT: LEEP conization with vaporization was performed for 86 CIN2+ cases. Our data suggest that combining LEEP conization and vaporization results in a higher estimated cumulative HPV clearance rate than LEEP alone. The clearance rate tended to be better in younger patients. Vaporization could provide a promising therapeutic option for VaIN2 associated with high-risk HPV infection. Treatment of CIN2+ and VaIN2 using ball electrode vaporization and LEEP conization appears feasible and effective, even in settings lacking specialized surgical devices. After conservative treatment of CINs or VaIN, HR-HPV persists in some cases even in the NILM state without dysplasia, and long-term follow-up is needed.