TITLE:
Nocardia cyriacigeorgica Infection in an Immunocompetent Patient: A Case Report from Italy and a Review of Recent Literature
AUTHORS:
Romano Mattei, Mariapia Niceforo, Moreno Ferroni, Laura Carrozzi, Massimiliano Desideri
KEYWORDS:
Nocardia cyriacigeorgica, Nocardia Pneumonia, Immunocompetent, Italy
JOURNAL NAME:
Open Journal of Medical Microbiology,
Vol.15 No.2,
June
27,
2025
ABSTRACT: Nocardiosis is prevalent among individuals with immunodeficiency or long-term use of immunosuppressive agents. However, in one third of cases, it can occur in immunocompetent patients [1]. Nocardia infections in immunocompetent patients represent a diagnostic challenge given the clinical and radiological similarity with infectious diseases and neoplasms [2]. We present the case of a Nocardia cyriacigeorgica pneumonia in an immunocompetent patient who had no history of immunosuppressive agent use, signs of immunodeficiency, or any concomitant diseases. In Italy, cases of Nocardia cyriacigeorgica infection are rarely reported in the literature, likely due to challenges in microbiological isolation and identification of this microorganism.