Sconza, C., Romano, D., Scaturro, D., Mauro, G.L., Leonardi, G., Alito, A., et al. (2024) Safety and Efficacy of Hybrid Cooperative Complexes of Sodium Hyaluronate and Sodium Chondroitin for the Treatment of Patients with Symptomatic Knee Osteoarthritis. Rheumatology and Therapy, 11, 381-395.
https://doi.org/10.1007/s40744-024-00643-8

has been cited by the following article:

• TITLE: Prospective Short-Term Observational Study of Glucosamine Complex with Chondroprotectors Effect in Adults with Diagnosed Knee and/or Hip Osteoarthritis

  AUTHORS: Maija Puce, Anna Medne-Simsone, Klinta Luize Sprudza

  KEYWORDS: Knee Osteoarthritis, Chondroprotection, Glucosamine, Chondroitin, Omega-3 Fatty Acids, Hyaluronic Acid, Collagen Type 2

  JOURNAL NAME: Health, Vol.17 No.4, April 25, 2025

  ABSTRACT: Objective: Osteoarthritis (OA) of the knee and/or hip is a chronic degenerative disease that severely impacts quality of life. Current treatments, such as NSAIDs, provide only symptomatic relief and are associated with significant side effects. This study evaluates whether short-term supplementation with a glucosamine complex (glucosamine, chondroitin, hyaluronic acid, omega-3, type II collagen) can improve OA symptoms. Methods: A prospective observational study recruited 200 OA patients from family physician practices in Latvia. Patients were divided into 1) Study group (n = 100) receiving Artroveron® 5in1 COMPLEX WITH OMEGA-3 (Glucosamine hydrochloride 300 mg, Omega-3 fatty acids 100 mg, Chondroitin sulfate 50 mg, Hyaluronic acid 20 mg, Type II collagen 20 mg); 2) Control group (n = 100) receiving no chondroprotectors. Pain levels were assessed at baseline and after 30 days using: Western Ontario and McMaster Universities Arthritis Index (WOMAC), Visual Analogue Scale (VAS). Results: Study group (glucosamine complex) had a statistically significant reduction in pain scores compared to the control group (p