TITLE:
In Vitro Evaluation of the Physicochemical Compatibility of Four Perfusion Mixtures: Case of an Ampoule of Paluject® in Glucose Serum with/or without Vogalene®
AUTHORS:
Alphonse Rodrigue Djiboune, Papa Mady Sy, Abdou Faye, Mamadou Soumboundou, Sidy Mouhamed Dieng, Mariama Dianké Diédhiou, Louis Augustin Diaga Diouf, Gora Mbaye, Mounibé Diarra
KEYWORDS:
Physicochemical Compatibility and Stability, Perfusion, Paluject®, Glucose Serum, Vogalene®
JOURNAL NAME:
Journal of Modern Physics,
Vol.15 No.13,
December
23,
2024
ABSTRACT: In this study, the physicochemical compatibility and stability of four drug mixtures were evaluated, and the common drug mixtures used in the treatment of severe malaria in children were simulated by gravity perfusion dynamic simulation experiment. The results showed that under experimental conditions, all drug mixtures exhibited clear transparency, stable density and refractive index, and pH values changed by no more than one unit, demonstrating compatibility and stability during the study period.