TITLE:
Signs of Aneurysm Formation Learned from Rubber Balloon Inflation
AUTHORS:
Fumio Nogata, Yasunari Yokota, Yoko Kawamura, Hiroyuki Morita, Yoshihiro Uno, William R. Walsh, Takahiko Kawamura, Nigishi Hotta, Kenji Kagechika
KEYWORDS:
Aneurysm Formation, Pressure-Inflation Characteristics, Elastic Instability, Expansion Signs, Saccular and Fusiform
JOURNAL NAME:
Journal of Biosciences and Medicines,
Vol.12 No.11,
November
28,
2024
ABSTRACT: Aneurysms can be classified into two main types based on their shape: saccular (spherical) and fusiform (cylindrical). In order to clarify the formation of aneurysms, we analyzed and examined the relationship between external force (internal pressure) and deformation (diameter change) of a spherical model using the Neo-Hookean model, which can be used for hyperelastic materials and is similar to Hooke’s law to predict the nonlinear stress-strain behavior of materials with large deformation. For a cylindrical model, we conducted an experiment using a rubber balloon. In the spherical model, the magnitude of the internal pressure Δp value is proportional to G (modulus of rigidity) and t (thickness), and inversely proportional to R (radius of the sphere). In addition, the maximum pressure Δp (max) is reached when λ (=expanded diameter/original diameter) is approximately 1.2, and the change in diameter becomes unstable (nonlinear change) thereafter. In the cylindrical model, localized expansion occurred at λ = 1.32 (λ = 1.98 when compared to the diameter at internal pressure Δp = 0) compared to the nearby uniform diameter, followed by a sudden rapid expansion (unstable expansion jump), forming a distinct bulge, and the radial and longitudinal deformations increased with increasing Δp, leading to the rupture of the balloon. Both models have a starting point where nonlinear deformation changes (rapid expansion) occur, so quantitative observation of the artery’s shape and size is important to prevent aneurysm formation.