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has been cited by the following article:

• TITLE: Factors Associated with Mother-to-Child Transmission of HIV at the Maternity Unit of the Castors Urban Health Center in Bangui

  AUTHORS: Thibaut Boris Clavaire Songo-Kette Gbekere, Gilles Davy Kossa-Ko-Ouakoua, Gertrude Rose De Lima Kogboma Wongo Guerengbo, Rodrigue Herman Doyama-Woza, Siméon Matoulou-M’bala Wa-Ngogbe, Alida Koirokpi, Sabrina Ouapou, Kelly Mbano-Dede Matike-Ayamboka, Josué Eezchiel Sandjima, Norbert Richard Ngbale

  KEYWORDS: Factors, Transmission, Mother-Child, HIV, Bangui

  JOURNAL NAME: Open Journal of Obstetrics and Gynecology, Vol.13 No.5, May 31, 2023

  ABSTRACT: Introduction: In spite of significant progress towards eliminating mother-to-child transmission (MCT) of HIV by 2025, trends in vertical mother-to-child transmission are still worrying in sub-Saharan African countries. This study aims to take stock of the factors associated with HIV MCT at the level of peripheral health training. Patients and Methods: This was a descriptive and analytical retrospective study, over a five-year period from January 1st, 2017 to December 31st, 2021. The study population was represented by HIV-positive women and their cared infants in the Parent-Child Transmission Prevention Unit (PCTP) of the Castors Urban Health Center (CUHC). Results: 288 medical records were selected out of a total of 347 HIV-positive mothers followed. HIV seroprevalence in the population of women who received PreNatal Consultation (PNC) during the study period was 8.2%. The HIV MCT rate was 3.7%. HIV+ mothers followed were mostly young (average age of 28), not living in a couple (96.9%), poorly educated (58.7%) and not engaged in income-generating activity (58.4%). They had all received triple therapy and the period of initiation of antiretroviral (ARV) therapy was in the majority of cases during the first trimester. Factors associated with MCT were: primiparity (OR = 18.4 [5.55 - 61.05]; Khi2 = 32.61; p 2 = 55.22; p 2 = 108.73; p 3 (OR = 14.12 [4.03 - 57.20]; Khi2 = 21.68; p 1000 copies/mm3 (OR = 8.85 [2.33 - 43.20]; Khi2 = 10.46; p = 0.001), prolonged labor (OR = 12.33 [3.45 - 57.25]; Khi2 = 18.47; p 2 = 40.60; p 2 = 5.96; p = 0.014), and artificial or mixed breastfeeding (OR = 0.01 [0.002 - 0.043]; Khi2 = 97.65; p Conclusion: Taking into account the risk factors for PCTP is essential if we want to achieve the goal of “Zero New Infections in Children by the year 2025”.