TITLE:
Haematology Parameters of Apparently Healthy Prospective Whole Blood Donors in a Nigerian Hospital Setting
AUTHORS:
Taiwo Modupe Balogun, Kingsley Aile, Athanasius Chika Nnamani, Olayinka Saidat Kareem, Adenekan Salu
KEYWORDS:
Whole Blood Donors, Selection, Haematology Parameters, CD4 +ve T Lymphocyte Counts, Nigeria
JOURNAL NAME:
Open Journal of Blood Diseases,
Vol.13 No.2,
May
18,
2023
ABSTRACT: Background: Adequate selection of a prospective whole blood donor protects his health
and safety of the recipient. Objectives: The main objective of this
study was to determine the haematology parameters of apparently healthy
prospective whole blood donors. Participants and Methods: This was a hospital based prospective
study carried out from August to October 2020 at the blood transfusion
unit of the Lagos State University Teaching Hospital (LASUTH), Ikeja, Nigeria. A structured pretested questionnaire was used for data collection. The
socio demographic status and the haematology parameters of apparently healthy
prospective whole blood donors who tested negative for HIV, hepatitis B and C
markers were captured. Obtained data were analysed with the statistical package
for the social scientist software version 20. Results: One hundred male (97.1%) and three female (2.9%) apparently healthy
prospective whole blood donors were studied. The median age of study subjects
was 30 years. Obtained median haematology parameter values were 13 g/dl,
40%, 4.9/nl and 203.9/nl for haemoglobin concentration, haematocrit, total
white cell and platelet counts respectively. The median values for the mean
corpuscular haemoglobin concentration (MCHC), mean corpuscular haemoglobin
(MCH) and mean corpuscular volume (MCV) of participants were 32.6 g/dl, 27.7 pg and
85.7 fl respectively. Observed prevalence of subnormal haematology parameters
for haemoglobin concentration, total white cells, platelets were 12.6%, 25.2%, and
13.6% respectively. Also subnormal values for MCHC, MCH, MCV were 11.7%, 26.2%,
and 16.5% respectively among prospective whole blood donors in this study. No
higher than normal haematology parameter values were observed. Median values
for erythrocyte sedimentation rate was 8.4 mm/hr. Conclusion: A significant percentage of apparently healthy prospective whole blood
donors had subnormal haematology parameters values. Obtained normal values in
our study are comparable with local reference range reports from previous
studies in Nigeria and other parts of Africa.
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