Article citationsMore>>
Chapel, H., Lucas, M., Lee, M., Bjorkander, J., Webster, D., Grimbacher, B., et al. (2008) Common Variable Immunodeficiency Disorders: Division into Distinct Clinical Phenotypes. Blood, 112, 277-286.
https://doi.org/10.1182/blood-2007-11-124545
has been cited by the following article:
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TITLE:
Late Onset Combined Immune Deficiency (LOCID) Revealed by a Haemolytic Anaemia in a Child: A Case Report
AUTHORS:
Amal Hamami, Maria Rkain, Madiha Benhachem, Ayyad Ghannam, Aziza Elouali, Abdeladim Babakhoua, Noufissa Benajiba
KEYWORDS:
Haemolytic Anaemia, LOCID, Immune Deficiency, Child
JOURNAL NAME:
Open Journal of Pediatrics,
Vol.13 No.3,
May
15,
2023
ABSTRACT: Variable
Common Immune Deficiency (VCID) is a very heterogeneous condition both
clinically and immunologically. It is a group of molecular abnormalities responsible for a defect in antibody
production leading to hypogammaglobulinemia often associated with
autoimmune and/or lymphoproliferative manifestations. Late Onset Combined Immune Deficiency (LOCID) is a
type of Variable Common Immune Deficiency (VCID) defined by a defect in
antibody production (IgG and IgA ± IgM
type), profound CD4 T-cell lymphopenia and frequent opportunistic infections. LOCID has been considered as
a distinct entity from VCID due to its particular clinical and immunological
profile.