TITLE:
Iron versus Iron and Vitamin B6 Supplementation in Treatment of Iron Deficiency Anemia during Second Trimester of Pregnancy: Quasi Experimental Trial
AUTHORS:
Mohamed Alaa Mohy Eldin El Ghannam, Sherif Hanafi Hussain, Alaa Mohamed Ali Osman, Sarah Safwat
KEYWORDS:
Vitamin B6, Iron Deficiency Anemia, Second Trimester, Hemoglobin
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.13 No.4,
April
28,
2023
ABSTRACT: Background: Anemia is
one of the most prevalent complications during pregnancy. It is commonly
considered a risk factor for poor pregnancy outcomes and can result in
complications that threaten the life of both mother and fetus, such as preterm
birth, and low birth weight. There is clear evidence to support prompt
treatment in all patients with iron deficiency anemia because it is known that
treatment improves quality of life and physical condition as well as alleviates
fatigue and cognitive deficits. Objective: The aim of the study was to evaluate the value of addition of vitamin B6 to
iron in treatment of iron deficiency anemia in pregnant women during the second trimester. Patients and Methods: The study was done by giving anemia pregnant women iron therapy and
vitamin B6 which represent group A and iron therapy alone which represents group B. For each pregnant woman, age,
parity and gestational history were taken before treatment. All pregnant women
took their allocated treatment regularly for three weeks after diagnosis of
iron deficiency anemia with complete blood picture and followed up after three
weeks. Results: Results
of the study revealed that there was no statistically significant difference
between the two groups of therapy according to the hemoglobin level before
treatment (p-value = 0.734), statistically significant higher mean value in after
treatment than before treatment (p-value = 0.048), there was a significant difference in the rate of change
of hemoglobin (p-value = 0.011) and body mass index (p-value 0.001). Conclusion: Iron and vitamin B6 seems to increase hemoglobin level more than
iron only. Thus, in pregnant women with iron deficiency anemia iron plus
vitamin B6 may be considered as a more effective alternative treatment than
iron only.