Gwede, C.K., Johnson, D., Sauder, B., Divan, H. and Trotti, A. (2001) Change in Quality of Life (QOL) and Function within the First Year in Patients Who Received Primary of Post-Operativeradiotheapy for Advanced Stage Head and Neck Cancer. International Journal of Radiation Oncology, 51, 408-409.
https://doi.org/10.1016/S0360-3016(01)02576-7

has been cited by the following article:

• TITLE: Evaluation of Quality of Life and Oral Changes of Patients in Head and Neck Radiotherapy: Observational Study

  AUTHORS: Emilly Silva e Silva, Gerlane Lima Oliveira, Ana Carolina Carneiro Cardoso, Isabella Melo Brito Ferreira, Marco Tulio Brazão-Silva, Douglas Magno Guimarães

  KEYWORDS: Adverse Reactions, Head and Neck Neoplasms, Radiotherapy

  JOURNAL NAME: Journal of Cancer Therapy, Vol.12 No.11, November 30, 2021

  ABSTRACT: Radiotherapy (RT) in the head and neck, despite coming from technological evolution, is challenged by the acute and late side effects of local irradiation, including permanent loss of saliva, osteoradionecrosis, dental caries induced by radiation and necrosis of the oral cavity, mucositis, xerostomia and secondary infections like candidiasis. Since these manifestations are limiting and the integrity of the vital organs contemplates the patient’s general health status, the oral health-related quality of life (OHRQoL) can be significantly affected by the treatment of head and neck cancer (HNC), since cancer can cause important changes in vital functions related to communication, food and social contact, causing disturbances in the patient’s life. An observational and longitudinal study was carried out with 16 cancer patients submitted to RT in the head and neck, between the years 2019-2020 with the objectives of collecting clinical and epidemiological data on the main oral changes caused by RT in the head and neck and correlating them with the impact on OHRQoL. To analyze the OHRQoL, the University of Washington’s Quality of Life Assessment questionnaire (UW-QOL) was applied once a week for 4 weeks and to observe oral manifestations, a dental clinic file standardized by the researchers was applied. The main oral manifestations clinically observed were hyposalivation, trismus and oral mucositis. The UW-QOL presented pain, chewing and taste as the main complaints reported by patients, however, appearance, salivation and chewing showed statistically significant differences over the weeks. The main manifestations observed were hyposalivation, trismus and oral mucositis, the physical limitations resulting from these manifestations impact the OHRQoL of cancer patients in terms of appearance, salivation and chewing.