TITLE:
Peripheral Neuropathy under Infliximab Therapy: About One Case
AUTHORS:
Fatima-Zahra Hamdoun, Hakima Abid, Nada Lahmidani, Mounia El Yousfi, Dafr-Allah Benajah, Mohammed El Abkari, Adil Ibrahimi
KEYWORDS:
Crohn’s Disease, Infliximab, Peripheral Neuropathy
JOURNAL NAME:
Open Journal of Gastroenterology,
Vol.10 No.9,
September
27,
2020
ABSTRACT: A-TNF
inhibitors are increasingly used in various inflammatory disorders. Multiple
side effects have been reported in recent years, particularly peripheral
neuropathies. We report a case of axonal neuropathy occurring after the start
of treatment with Infliximab. This is a 47 years old patient, followed for
Crohn’s
disease requiring treatment with Infliximab. Twenty-two weeks later, the patient
presented a grade 4 of axonal neuropathy. We concluded to a medicinal sensitive
neuropathy after elimination of other etiologies. Given the severity of the neurological symptoms, we
decided to change the therapeutic class.