TITLE:
Relationship between Uricemia and Other Biochemical Markers with the Materno-Fetal Complications during Pre-Eclampsia
AUTHORS:
B. D. Tshibuela, N. N. Kayembe, M. J. Muwonga, N. K. Nganga, N. Ngole, J. P. Elongi
KEYWORDS:
Uricemia, Biochemical Markers, Maternal-Fetal Complications, Pre-Eclampsia
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.7 No.13,
December
19,
2017
ABSTRACT: Goal: Determining the place of Uricemia associated with other
biochemical makers in the prediction of fetal-maternal complications during preeclampsia. Material and method: This is a prospective, cross-sectional study of 75 pre-eclamptic
women in three maternities in Kinshasa, Democratic Republic of Congo, during the January to December
2013. The values of the following biochemical markers: uricemia, proteinuria and
creatinemia were correlated with maternal and fetal prognosis. Results: This study showed that hyper uricemia associated with massive proteinuria and
a high creatinine level correlated with an unfavorable pregnancy outcome and the
occurrence of major materno-fetal complications such as eclampsia (X-squared
= 24.3598, ddl = 2, p-value = 0.000005) and low birth weight (p = 0.001, R2 = 0.08). Conclusion: In view of these results, it appears necessary to ensure these biochemical markers
systematically in the monitoring of pre-eclampsia.