TITLE:
The Unexpected Bioenergetic Function of Neuromelanin. Implications in the Biology of Learning and Memory
AUTHORS:
Arturo Solis Herrera, Ruth I. Solis Arias
KEYWORDS:
Hydrogen, Energy, Memory, Eukaryotic Cell, Neurons, Cerebral Cortex, Substantia Nigra
JOURNAL NAME:
Natural Science,
Vol.9 No.11,
November
30,
2017
ABSTRACT: Progressive
Recent Memory loss is the main complaint in Alzheimer’s disease patients. There
is not a simple or congruous explanation yet due to highly complex mechanisms
by which the Central Nervous System store and organize experiences every day,
developed along 4 billion years of evolution; thereby learning and memory are
poorly understood biological processes. The finding of the unsuspected
intrinsic property of melanin to transforms light into chemical energy through
water dissociation, as chlorophyll in plants; opens a new and wider horizon in
the form in which the CNS generate and distribute chemical energy transporting
it through molecular hydrogen produced by substantia nigra of mesencephalon and
other pigmented structures. The mechanisms by which human modifies their
behavior through learning and memory remain a mystery despite several decades
of research. However, theunexpected role of melanin molecule
bioenergetics of first order, very above the chlorophyll and glucose, indicatesthat the study of the
fascinating processes involved in learning and memory several levels, needs to
be started with the study of the generation and distribution of energy
neuro-melanin-releasing to all the brain. In this article, we explain
succinctly, the way hydrogen molecular (H2)-gas-, from the
dissociation of water by the neuro melanin, moves from its source and permeates
easily through the different structures of the Central Nervous System, as well
as be the smaller atom, does not combine with water, moving through it in
accordance with the laws of the simple diffusion. Molecular hydrogen is the
main carrier of energy that nature uses in the entire universe, so that, once the neuro
melanin separates it from the water, this displaces transporting its precious
cargo of energy and its remarkable antioxidant capacity capable of reduce
oxygen and form water.