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has been cited by the following article:

• TITLE: Age Does Not Affect the Induction of Mortality by the Foodborne Pathogen Salmonella enterica in Caenorhabditis elegans

  AUTHORS: Dawn M. F. Burns, James M. Harper, Aaron M. Lynne

  KEYWORDS: Salmonella enterica, Caenorhabditis elegans, Aging, Infection

  JOURNAL NAME: Advances in Microbiology, Vol.7 No.10, October 31, 2017

  ABSTRACT: Salmonella is a common cause of foodborne illness within the United States with the severity of the infection being a factor of both the age and overall health of the infected individual. The nematode worm Caenorhabditis elegans has proven to be a useful model to study infection dynamics of pathogenic bacteria, including Salmonella enterica, and its short lifespan makes it a powerful model system to assess the effect of organismal age on infection severity. In this study, we infected C. elegans with each of 6 serovars of S. enterica at 1, 3 or 5 days of worm age and monitored their survival. Worms infected with E. coli OP50 were used as a control. Infection with S. enterica resulted in a significant reduction in mean longevity relative to OP50 (p