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https://doi.org/10.1023/A:1010102422381

has been cited by the following article:

• TITLE: Thermal Decomposition Kinetics of Ursodeoxycholic Acid Drug Crystal

  AUTHORS: S. Ramukutty, R. Jeyasudha, E. Ramachandran

  KEYWORDS: Thermal Analysis, Thermal Decomposition Kinetics, Ursodeoxycholic Acid

  JOURNAL NAME: Journal of Crystallization Process and Technology, Vol.7 No.4, September 30, 2017

  ABSTRACT: The crystallization of ursodeoxycholic acid drug crystals in gel by reduction of solubility method is the first of its kind to be reported in literature. Monoclinic crystalline form of the structure was confirmed using single crystal X-ray diffraction analysis. This report deals with the kinetic analysis made from the thermogravimetric analysis/differential thermal analysis (TGA/DTA) data using Coats-Redfern (CR) relation. Thermodynamic parameters were also determined. Arrhenius equation for ursodeoxycholic acid was derived as k = 3.10 × 1010 e−172581/RT mol−1•s−1.