TITLE:
Plaque Psoriasis: Understanding Risk Factors of This Inflammatory Skin Pathology
AUTHORS:
Audrey Bélanger, Catiúscia Padilha de Oliveira, Maxim Maheux, Roxane Pouliot
KEYWORDS:
Plaque Psoriasis, Clinical Phenotypes, Comorbidities, Genotype-Phenotype Correlation, Susceptibility Gene
JOURNAL NAME:
Journal of Cosmetics, Dermatological Sciences and Applications,
Vol.6 No.2,
May
9,
2016
ABSTRACT: Covering the entire human body, the skin is considered to be one of the most
important organs, since it is the first line of protection against chemical and
biological external agents. Although the skin protects tissues and organs against
external aggression, it can still be unbalanced by various skin diseases, such as
psoriasis. This non-contagious inflammatory dermatosis is characterized by the occurrence
of erythematous lesions of various sizes covered with whitish scales. This scaling
of the skin is the result of a rapid renewal of the epidermis, occurring over five
to seven days instead of 28 days. Psoriasis
vulgaris, or plaque psoriasis, is the most common form of this disease and is
therefore commonly referred to by the term “psoriasis”. This work is a review of
the literature on plaque psoriasis, aiming at a better comprehension of the pathology
at the histological level, but also to understand the genetic and environmental
factors associated with this inflammatory dermatosis.