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Nishizawa, T., Ueda, A., Nakano, T., Nishizawa, A., Miura, T., Asayama, M., Fujii, K., Harada, K.-I. and Shirai, M. (2011) Characterization of the Locus of Genes Encoding Enzymes Producing Heptadepsipeptide Micropeptin in the Unicellular Cyanobacterium Microcystis. Journal of Biochemistry, 149, 475-485.
http://dx.doi.org/10.1093/jb/mvq150
has been cited by the following article:
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TITLE:
Phylogenetic Analysis of Frequent Recombinant Region in Micropeptin Biosynthetic Gene Cluster among the Genus Microcystis
AUTHORS:
Tomoyasu Nishizawa, Takamasa Miura, Ayana Futamura, Makoto Shirai
KEYWORDS:
Cyanobacteria, Microcystis, Micropeptin Biosynthetic Gene, Phylogenetic Analysis
JOURNAL NAME:
Advances in Microbiology,
Vol.6 No.5,
April
27,
2016
ABSTRACT: The gene cluster for the biosynthetic of a nonribosomal peptide, cyanopeptolins and micropeptin
(MCN), was identified in Microcystis strains and halogenated MCN-producing Microcystis were
found to possess the halogenase gene, mcnD, between nonribosomal peptide synthetase genes, mcnC and mcnE. A comparative sequence analysis of the mcn gene cluster between halogenated
and non-halogenated MCN-producing strains revealed mosaic sequence traces from mcnD in the
non-coding region between mcnC and mcnE in the latter strains. A phylogenetic analysis based on
a 170-bp non-coding region including the mcnD traces suggests that the recombination events occurred
in a particular region of the Microcystis’ mcn gene. This study provides novel insight into
the ecological patterning of widespread Microcystis species.