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has been cited by the following article:

• TITLE: Morphofunctional Characteristics of Pulmonary Surfactant System and Its Effect on Immune Cells in Influenza A (H1N1) Pathogenesis

  AUTHORS: A. V. Kovner, O. V. Potapova, V. A. Shkurupy, A. M. Shestopalov

  KEYWORDS: Influenza A (H1N1) Virus, Pulmonary Surfactant system, SP-A, M1/M2 Macrophages, Antiviral Defense

  JOURNAL NAME: Open Journal of Pathology, Vol.6 No.1, January 6, 2016

  ABSTRACT: There is an annual increase of influenza-related SARI cases in winter months. Despite the high relevance of this problem, influenza pathogenesis and the role of surfactant system and its SP-A (surfactant protein A) enzyme in antiviral defense remain poorly understood. SP-A activates macrophage M1 polarization and triggers an antiviral response due to the activation of T-cells and dendritic cells. Therefore, surfactant system is an important element of infection protection and a promising therapeutic target.