TITLE:
Case Report: A Laparoscopic Treated Case of Deep Infiltrating Endometriosis with Vaginal Invasion Diagnosed by Vaginal Cytology
AUTHORS:
Kenji Niwa, Ryuichiro Yano, Yui Hatanaka, Sakae Mori, Yoshio Yamaguchi, Minako Mori, Yoko Ueda, Takuji Tanaka
KEYWORDS:
Vaginal Endometriosis, Cytology, Immunohistochemistry, Laparoscopic Surgery
JOURNAL NAME:
Open Journal of Pathology,
Vol.5 No.3,
July
9,
2015
ABSTRACT: A recently observed case of deep
infiltrating endometriosis with its vaginal invasion diagnosed by vaginal
cytology is reported. A 28-year-old Japanese woman complained of a severe
dysmenorrhea. Left ovarian endometriotic cyst and deep infiltrating
endometriosis were suspected. Two red-spots were also present in the posterior
fornix of vagina. Vaginal cytology withcytokeratin (CK)
7-immunocytochemistry suggested the presence of infiltrating endometriosis. She
underwent left ovarian cystectomy and resection of thickened uterosacral
ligaments with vaginal endometriotic spots, under a laparoscope, based on the
diagnosis of endometriotic cyst. Histopathology revealed DIE with vaginal
invasion. Immunostaining for CK7 was positive for endometriotic cyst, while
CK20 was negative. The stromal cells in endometriosis were
immunohistochemically positive for CD10. The vaginal fornix was well-healed one
month later the surgery. Postoperatively, she got pregnant with her natural
intercourse and delivered a healthy 2138 g girl at 36 weeks of gestation.