TITLE:
Bioinspired-Interpenetrating Network (IPNs) Hydrogel (BIOF-INPs) and TMD in Vitro: Bioadhesion, Drug Release and Build in Free Radical Detection and Defense
AUTHORS:
Victoria Tamara Perchyonok, Vanessa Reher, Nicolaas J. Basson, Shengmiao Zhang, Sias R. Grobler
KEYWORDS:
TMD, Functionalized IPNs, Bio-Adhesion, Drug Release, Build in Free Radical Detection and Defense
JOURNAL NAME:
Open Journal of Stomatology,
Vol.5 No.3,
March
4,
2015
ABSTRACT: In
this work, Bioactive-functionalized interpenetrating network (IPNs) hydrogel
(BIOF-INPs) were prepared and investigated in
vitro for the free radical detection/defense, therapeutic release as well
as shear bond strength to dentine, ability to re-mineralize surface of the
dentin after application of these bio-inspired materials using a biologically
inspired mineralization process in vitro as well as investigating antimicrobial properties of the BIOF-INPs against S. aureous. The aim of this
investigation was to evaluate the suitability and flexibility of the designer
materials to act as an “in vitro”
probe to gain insights into molecular origin of TMD and associated disorders.