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http://dx.doi.org/10.1016/j.rdc.2007.12.002

has been cited by the following article:

• TITLE: Primary Cardiac Involvement in Scleroderma and Role of Cardiac MRI

  AUTHORS: Kashif Hussain, Robert C. Stansbury

  KEYWORDS: Scleroderma, Primary Cardiac Involvement, Cardiac MRI

  JOURNAL NAME: International Journal of Clinical Medicine, Vol.5 No.20, November 18, 2014

  ABSTRACT: Systemic sclerosis (scleroderma) is a connective tissue disease characterized by vascular dysfunction and fibrosis that can affect multiple organ systems. We present case of primary cardiac involvement and the diagnostic role of cardiac MRI. Cardiovascular magnetic resonance imaging (MRI) is an accurate, quantitative method for the non-invasive assessment of myocardial perfusion. The presence of clinically apparent myocardial involvement in scleroderma portends a very poor prognosis. One study of US veterans found that clinical cardiac disease in scleroderma was associated with a 70% mortality rate at five years. Management of heart failure and conduction system abnormalities in scleroderma is similar to other cardiac disease. It includes afterload reduction, beta-blockade, defibrillator placement, etc. Patients with reduced cardiac function and normal coronary arteries may benefit from increased immune suppresion.