TITLE:
Preparation of Microcapsules Containing Triple Core Materials with Interfacial Condensation Reaction
AUTHORS:
Yoshinari Taguchi, Mikihiko Aoki, Masato Tanaka
KEYWORDS:
Triple Core Materials-Containing-Microcapsule, Multiple Emulsions, α-Tocopherol, Calcium Chloride, Dissolution Heat, Hydroxy Propyl Methyl Cellulose, Tannic Acid
JOURNAL NAME:
Journal of Cosmetics, Dermatological Sciences and Applications,
Vol.4 No.4,
September
10,
2014
ABSTRACT: In this manuscript, we describe the novel
method for preparing the microcapsules containing α-tocopherol oil droplets as the first core material, calcium
chloride powder as the second core material and the fine water droplets as the
third core material by the interfacial condensation reaction between hydroxyl
propyl methyl cellulose and tannic acid. The interfacial condensation reaction
was performed between hydroxyl propyl methyl cellulose dissolved in the
continuous water phase and tannic acid dissolved in the inner fine water
droplets as the third core material. The calcium chloride powder as the second
core material was dispersed in the α-tocopherol
oil droplet as the first core material beforehand. The α-tocopherol oil containing the second and the third core materials
was dispersed in the continuous water phase to form the [(S + W)/O/W] emulsion.
The α-tocopherol oil as the first
core material was microencapsulated
satisfactorily and the contents of the second core material were increased with
the concentration of stearic acid as the oil soluble stabilizer. The mechanical
strength of microcapsules increased with the concentration of hydroxyl propyl methyl cellulose. Thermal energy could be
released by breaking the microcapsules in water and by dissolving calcium
chloride in the continuous water phase.