Kondo, H., Asamura, H., Suemasu, K., Goya, T., Tsuchiya, R., Naruke, T., Yamagishi, K. and Uei, Y. (1993) Prognostic Significance of Pleural Lavage Cytology Immediately after Thoracotomy in Patients with Lung Cancer. Journal of Thoracic and Cardiovascular Surgery, 106, 1092-1097.

has been cited by the following article:

• TITLE: Five-Year Survivors of Non-Small Cell Lung Cancer Patients with Positive Pleural Lavage Cytology

  AUTHORS: Masaki Tomita, Takanori Ayabe, Eiichi Chosa, Kunihide Nakamura

  KEYWORDS: Pleural Lavage Cytology Positive; Non-Small Cell Lung Cancer; 5-Year Survivor

  JOURNAL NAME: Advances in Lung Cancer, Vol.3 No.1, February 24, 2014

  ABSTRACT: Background: The pleural lavage cytology (PLC) for non-small cell lung cancer (NSCLC) patients has been reported as a significant prognostic factor. The aim of this study is to clarify the clinicopathological characteristics of 5-year survivors of patients with positive PLC. Methods: Among 401 resected NSCLC patients, 30 (7.48%) patients with positive PLC were reviewed retrospectively. Results: Only 7 of 30 patients (23.3%) survived more than 5-year. There were no differences in age, gender, histology, pT status and pN status between 5-year survivors and non-survivors. On the other hand, the serum carcinoembryonic antigen (CEA) level was significantly higher in non-survivors. Among these 5-year survivors, 4 of 7 patients died of NSCLC recurrences more than 5 years after surgery. Remaining 3 patients survived without cancer recurrences. Interestingly these 3 survivors had not received any adjuvant therapies after surgery. Conclusion: None of the 5-year survivor with positive PLC had high serum CEA level. Furthermore 5-year survival did not equal to cure in NSCLC patients with positive PLC.