TITLE:
Polychlorinated biphenyl congeners (PCBs) in nursing primiparous and multiparous women
AUTHORS:
Sobia Khwaja, Rubina Mushtaq, Rehana Mushtaq, Masarrat J. Yousuf, Fozia Tabbassum
KEYWORDS:
Poly Chlorinated Biphenyls; Primipara; Multipara; Breast Milk; Contamination; MSPD and ECD; Pakistan
JOURNAL NAME:
Advances in Bioscience and Biotechnology,
Vol.4 No.11,
November
11,
2013
ABSTRACT:
Impact of PCBs was studied as a major source
of physiological effects even very low concentration of PCBs transferred to the
infants by mother’s milk. Milk samples were collected from
primipara and multipara women. A significant variation pattern was observed in
the level of PCB congeners, as PCBs are
lipophilic in nature, another possibility arises that great deals of residues
are passed on to infants through mother’s milk. A technique was developed to find
out polychlorinated biphenyls (PCB) in breast milk. PCBs were extracted by
Matrix Solid-Phase Dispersion (MSPD) and analyzed by Gas Chromatography with
Electron Capture Detector. The precision (RSD ·L-1),
the chi square analysis at p ≤ 0.05 has shown that the PCB level was higher in
multipara as compared to primipara. The analysis of the thirty samples
revealed PCB levels above 6.85 μg·L-1 in breast milk samples by
analyses of a mixture of PCB congeners. All PCB congeners (28, 52, 101, 123 (+149),
118, 114, 153, 105, 138 (+163), 167, 156 (+171), 157, 180, 170, 189) were found
at high level in primiparous and multiparous. Thus, a high correlation between
the contamination of breast milk and environmental pollution of PCBs was observed.