TITLE:
CT Perfusion Imaging Predicts One-Month Outcome in Patients with Acute Spontaneous Hypertensive Intracerebral Hemorrhage
AUTHORS:
Huazhi Xu, Weijian Chen, Meihao Wang, Guoquan Cao, Yuxia Duan, Jiying Zhu
KEYWORDS:
Cerebral Hemorrhage; X-Ray Computed Tomography; Perfusion Imaging; Outcome
JOURNAL NAME:
Advances in Computed Tomography,
Vol.2 No.3,
September
26,
2013
ABSTRACT:
Purpose: Little is known about the relationship between perihematomal
perfusion parameters in acute spontaneous hypertensive intracerebral hemorrhage
patients and recent outcome. The purpose of this study was to evaluate the relationship
between the perfusion parameters of the perihematomal brain tissue and the
recent prognosis of patients with acute spontaneous hypertensive intracerebral
hemorrhage (shICH) using CT perfusion (CTP) imaging. Methods: Twenty-six
patients with clinical and CT diagnosed supratentorial shICH received
CTP scanning within 8 - 19 h after symptom onset. At the maximum levels of
the hematoma, cerebral blood flow (CBF), cerebral blood volume (CBV) and mean
transit time (MTT) of perihematomal area (isodense within 1cm rim of perilesion area on plain CT) and contralateral
mirrored hemisphere were measured, and rCBF, rCBV, rMTT were calculated (ipsilateral/contralateral).
The one-month follow-up in accordance with daily living table (Barthel index,
BI) by telephone was recorded. Results: The CBV, CBF, and MTT values of
perihematoma area were (1.61 ± 1.53) ml·100 g-1,
(16.48 ± 12.58) ml·100 g-1·min-1,
and (9.12 ± 2.57) s, respectively. (For more information,please refer to the PDF)