TITLE:
Experimental Haematobiochemical Alterations in Broiler Chickens Fed with T-2 Toxin and Co-Infected with IBV
AUTHORS:
T. Yohannes, A. K. Sharma, S. D. Singh, V. Sumi
KEYWORDS:
Anaemia; Hypoproteinenemia; IBV; Lymphocytopenia; T-2 Toxin; Thrombocytopenia
JOURNAL NAME:
Open Journal of Veterinary Medicine,
Vol.3 No.5,
August
20,
2013
ABSTRACT:
The purpose of this experimental study was
to evaluate and record the effects of T-2 toxicity alone and in association
with IBV infection on haematobiochemical parameters. A total of 128
one-week-old chicks were divided into four groups of 32 birds each and were
treated respectively with T-2 toxin alone, IBV alone, T-2 toxin and co-infected
with IBV, and no treatment (control) for a period of 6 weeks. Haematologically,
the birds treated with T-2 toxin developed anaemia as indicated by significant
decrease in haemoglobin levels, total erythrocyte counts and packed cell volume
values; leucopenia, lymphocytopenia heterophilia and thrombocytopenia. The IBV
infected birds exhibited lymphocytophilia and heteropoenia; the degrees of
severity of leucopenia, lymphocytopenia heterophilia and thrombocytopenia were
more pronounced in T-2+IBV groups. The serum biochemistry revealed
hypoproteinemia and hypoalbuminemia in all the treated groups consistently.
Besides, hypoglobulinemia and increased levels of alanine aminotransferase in T-2+IBV, and increased levels of alkaline phosphatase in toxin group alone were
recorded. The changes in biochemical parameters were more in magnitude in the combination treatment group and
their severity increased with duration of treatment. It was concluded that T-2
toxin made the birds more susceptible to IBV infection.